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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK2
All Species:
21.52
Human Site:
S133
Identified Species:
39.44
UniProt:
Q6A1A2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6A1A2
XP_002343452
396
44765
S133
E
K
L
Y
F
G
L
S
Y
A
K
N
G
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
S164
E
K
L
Y
F
G
L
S
Y
A
K
N
G
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
S163
E
K
L
Y
F
G
L
S
Y
A
K
N
G
E
L
Rat
Rattus norvegicus
O55173
559
63591
S163
E
K
L
Y
F
G
L
S
Y
A
K
N
G
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
R77
G
E
L
L
K
Y
I
R
K
I
G
S
F
D
E
Chicken
Gallus gallus
Q6U1I9
432
48872
D178
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
Frog
Xenopus laevis
Q6GPN6
434
49096
D180
S
R
L
Y
F
I
L
D
Y
I
N
G
G
E
L
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
D179
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
Q344
D
R
L
C
F
V
M
Q
Y
V
N
G
G
E
L
Honey Bee
Apis mellifera
XP_394208
537
61368
S126
E
R
L
Y
F
V
L
S
Y
A
K
N
G
E
L
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
G152
A
R
I
Y
F
V
I
G
L
V
E
N
G
D
L
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
S162
Y
K
L
Y
F
G
L
S
L
A
K
R
G
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
E258
S
S
L
Y
F
L
L
E
Y
A
P
N
G
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
62.8
N.A.
62.9
63.1
N.A.
69.4
31
31.1
31.1
N.A.
23.2
41.5
23.7
47.5
Protein Similarity:
100
N.A.
N.A.
64.4
N.A.
64.7
64.9
N.A.
72.9
49
50.4
50.5
N.A.
37.9
53
39.7
56.5
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
60
53.3
60
N.A.
40
86.6
33.3
80
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
33.3
66.6
60
66.6
N.A.
60
93.3
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
0
0
0
0
0
24
0
0
0
0
0
24
0
% D
% Glu:
39
8
0
0
0
0
0
8
0
0
8
0
0
77
8
% E
% Phe:
0
0
0
0
93
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
8
0
0
0
0
39
0
8
0
0
8
31
93
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
16
0
0
31
0
0
0
0
0
% I
% Lys:
0
54
0
0
8
0
0
0
8
0
47
0
0
0
0
% K
% Leu:
0
0
93
8
0
8
77
0
16
0
0
0
0
0
85
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
31
54
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
31
0
0
0
0
0
8
0
0
0
8
0
0
0
% R
% Ser:
16
8
0
0
0
0
0
47
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
39
0
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
85
0
8
0
0
77
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _