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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDPK2 All Species: 25.76
Human Site: S223 Identified Species: 47.22
UniProt: Q6A1A2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6A1A2 XP_002343452 396 44765 S223 V G T A Q Y V S P E L L T E K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537000 560 63701 S254 V G T A Q Y V S P E L L T E K
Cat Felis silvestris
Mouse Mus musculus Q9Z2A0 559 63740 S253 V G T A Q Y V S P E L L T E K
Rat Rattus norvegicus O55173 559 63591 S253 V G T A Q Y V S P E L L T E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518589 320 36424 L159 Q Y V S P E L L T E K S A C K
Chicken Gallus gallus Q6U1I9 432 48872 A266 C G T P E Y L A P E V L H K Q
Frog Xenopus laevis Q6GPN6 434 49096 A268 C G T P E Y L A P E V L H K Q
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 A267 C G T P E Y L A P E V L H K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INB9 611 68466 A432 C G T P E Y L A P E V L D D N
Honey Bee Apis mellifera XP_394208 537 61368 V244 F V G T A Q Y V S P E L L T D
Nematode Worm Caenorhab. elegans Q9Y1J3 636 71898 S278 V G T A L Y V S P E M L A D G
Sea Urchin Strong. purpuratus XP_786576 539 61612 S255 V G T A Q Y V S P E L L T E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12236 1081 121642 S357 V G T A E Y V S P E L L N D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 62.8 N.A. 62.9 63.1 N.A. 69.4 31 31.1 31.1 N.A. 23.2 41.5 23.7 47.5
Protein Similarity: 100 N.A. N.A. 64.4 N.A. 64.7 64.9 N.A. 72.9 49 50.4 50.5 N.A. 37.9 53 39.7 56.5
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 13.3 40 40 40 N.A. 40 6.6 66.6 100
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 26.6 80 80 80 N.A. 73.3 6.6 80 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 27.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 54 8 0 0 31 0 0 0 0 16 0 0 % A
% Cys: 31 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 8 24 8 % D
% Glu: 0 0 0 0 39 8 0 0 0 93 8 0 0 39 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 85 8 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 8 0 0 24 47 % K
% Leu: 0 0 0 0 8 0 39 8 0 0 47 93 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 31 8 0 0 0 85 8 0 0 0 0 0 % P
% Gln: 8 0 0 0 39 8 0 0 0 0 0 0 0 0 24 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 54 8 0 0 8 0 0 8 % S
% Thr: 0 0 85 8 0 0 0 0 8 0 0 0 39 8 0 % T
% Val: 54 8 8 0 0 0 54 8 0 0 31 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 85 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _