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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDPK2 All Species: 8.79
Human Site: S37 Identified Species: 16.11
UniProt: Q6A1A2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6A1A2 XP_002343452 396 44765 S37 E P R P G A G S L Q H A Q P P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537000 560 63701 S67 E S R P S T N S L Q H T T Q P
Cat Felis silvestris
Mouse Mus musculus Q9Z2A0 559 63740 P65 E A R P S T N P L Q Q H P A Q
Rat Rattus norvegicus O55173 559 63591 P65 E A R P S T N P L Q Q H P A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518589 320 36424
Chicken Gallus gallus Q6U1I9 432 48872 S90 Q I N L G P S S N P H A K P S
Frog Xenopus laevis Q6GPN6 434 49096 S92 Q I N L G P S S N P H A K P S
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 N38 K Q R K M G L N D F I Q K L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INB9 611 68466 Y43 S N I I N I I Y S Q S T H P N
Honey Bee Apis mellifera XP_394208 537 61368 T38 L T T I N P P T H K R T P K D
Nematode Worm Caenorhab. elegans Q9Y1J3 636 71898 P46 E S E N S L S P V T A E D L I
Sea Urchin Strong. purpuratus XP_786576 539 61612 S68 P R S A T S P S P S P S S T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12236 1081 121642 E163 S Q K P I A K E S S K A Q K N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 62.8 N.A. 62.9 63.1 N.A. 69.4 31 31.1 31.1 N.A. 23.2 41.5 23.7 47.5
Protein Similarity: 100 N.A. N.A. 64.4 N.A. 64.7 64.9 N.A. 72.9 49 50.4 50.5 N.A. 37.9 53 39.7 56.5
P-Site Identity: 100 N.A. N.A. 53.3 N.A. 33.3 33.3 N.A. 0 33.3 33.3 6.6 N.A. 13.3 0 6.6 6.6
P-Site Similarity: 100 N.A. N.A. 53.3 N.A. 33.3 33.3 N.A. 0 46.6 46.6 26.6 N.A. 13.3 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 27.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 8 0 16 0 0 0 0 8 31 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 8 % D
% Glu: 39 0 8 0 0 0 0 8 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 24 8 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 31 16 8 0 0 % H
% Ile: 0 16 8 16 8 8 8 0 0 0 8 0 0 0 8 % I
% Lys: 8 0 8 8 0 0 8 0 0 8 8 0 24 16 0 % K
% Leu: 8 0 0 16 0 8 8 0 31 0 0 0 0 16 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 16 8 16 0 24 8 16 0 0 0 0 0 16 % N
% Pro: 8 8 0 39 0 24 16 24 8 16 8 0 24 31 16 % P
% Gln: 16 16 0 0 0 0 0 0 0 39 16 8 16 8 16 % Q
% Arg: 0 8 39 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 16 16 8 0 31 8 24 39 16 16 8 8 8 0 31 % S
% Thr: 0 8 8 0 8 24 0 8 0 8 0 24 8 8 0 % T
% Val: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _