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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK2
All Species:
4.85
Human Site:
S386
Identified Species:
8.89
UniProt:
Q6A1A2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6A1A2
XP_002343452
396
44765
S386
C
S
R
K
G
R
V
S
V
P
L
R
Q
A
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
L441
F
S
E
D
E
K
R
L
L
L
E
K
Q
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
L440
F
S
E
D
E
K
R
L
L
L
E
K
Q
A
G
Rat
Rattus norvegicus
O55173
559
63591
L440
F
S
E
D
E
K
R
L
L
L
E
K
Q
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
L313
A
L
E
S
S
Q
V
L
S
V
V
L
A
M
Q
Chicken
Gallus gallus
Q6U1I9
432
48872
Y424
E
A
F
L
G
F
S
Y
A
P
P
V
D
S
F
Frog
Xenopus laevis
Q6GPN6
434
49096
Y426
E
A
F
M
G
F
S
Y
A
P
P
M
E
S
Y
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Y425
E
A
F
L
G
F
S
Y
A
P
A
M
D
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
T603
G
T
S
S
H
I
S
T
S
T
S
L
A
S
M
Honey Bee
Apis mellifera
XP_394208
537
61368
W483
V
L
K
G
E
I
P
W
S
P
E
L
R
V
E
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
Q528
V
P
W
T
P
C
M
Q
V
E
L
K
N
S
G
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
P490
K
G
E
I
P
W
S
P
Q
L
K
V
E
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
D897
L
K
Y
E
L
E
Y
D
I
N
L
R
Q
Q
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
62.8
N.A.
62.9
63.1
N.A.
69.4
31
31.1
31.1
N.A.
23.2
41.5
23.7
47.5
Protein Similarity:
100
N.A.
N.A.
64.4
N.A.
64.7
64.9
N.A.
72.9
49
50.4
50.5
N.A.
37.9
53
39.7
56.5
P-Site Identity:
100
N.A.
N.A.
20
N.A.
20
20
N.A.
6.6
13.3
13.3
13.3
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
N.A.
N.A.
40
N.A.
40
40
N.A.
20
26.6
33.3
26.6
N.A.
20
20
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
0
0
0
0
0
0
24
0
8
0
16
39
0
% A
% Cys:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
24
0
0
0
8
0
0
0
0
16
0
0
% D
% Glu:
24
0
39
8
31
8
0
0
0
8
31
0
16
0
8
% E
% Phe:
24
0
24
0
0
24
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
0
8
31
0
0
0
0
0
0
0
0
0
31
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
16
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
8
8
8
0
24
0
0
0
0
8
31
0
0
8
% K
% Leu:
8
16
0
16
8
0
0
31
24
31
24
24
0
0
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
16
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
8
0
0
16
0
8
8
0
39
16
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
8
0
0
0
39
8
8
% Q
% Arg:
0
0
8
0
0
8
24
0
0
0
0
16
8
0
0
% R
% Ser:
0
31
8
16
8
0
39
8
24
0
8
0
0
39
8
% S
% Thr:
0
8
0
8
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
16
0
0
0
0
0
16
0
16
8
8
16
0
8
0
% V
% Trp:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
24
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _