Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDPK2 All Species: 19.7
Human Site: Y306 Identified Species: 36.11
UniProt: Q6A1A2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6A1A2 XP_002343452 396 44765 Y306 G C E E M E G Y G P L K A H P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537000 560 63701 Y337 G C E E M G G Y S P L R A H P
Cat Felis silvestris
Mouse Mus musculus Q9Z2A0 559 63740 Y336 G C E E M E G Y G P L K A H P
Rat Rattus norvegicus O55173 559 63591 Y336 G C E E M E G Y G P L K A H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518589 320 36424 E234 T K R L G C E E M G A Y G P L
Chicken Gallus gallus Q6U1I9 432 48872 K344 R T K R L G A K E D F T E I K
Frog Xenopus laevis Q6GPN6 434 49096 N347 T K R I G A K N D F M E I K N
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 D346 T K R L G F T D D F T E I K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INB9 611 68466 V514 L G G G K D D V K E I Q A H P
Honey Bee Apis mellifera XP_394208 537 61368 Y329 Q D E H G A G Y P S I R A H P
Nematode Worm Caenorhab. elegans Q9Y1J3 636 71898 S355 D P S T R I T S Q E L M A H K
Sea Urchin Strong. purpuratus XP_786576 539 61612 Y338 G C D E C G G Y P A L K A H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12236 1081 121642 D791 D L Q L L E D D Y R I E G G D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 62.8 N.A. 62.9 63.1 N.A. 69.4 31 31.1 31.1 N.A. 23.2 41.5 23.7 47.5
Protein Similarity: 100 N.A. N.A. 64.4 N.A. 64.7 64.9 N.A. 72.9 49 50.4 50.5 N.A. 37.9 53 39.7 56.5
P-Site Identity: 100 N.A. N.A. 80 N.A. 100 100 N.A. 0 0 0 0 N.A. 20 40 20 66.6
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 100 100 N.A. 0 13.3 13.3 6.6 N.A. 40 53.3 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 27.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 16 8 0 0 8 8 0 62 0 0 % A
% Cys: 0 39 0 0 8 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 8 0 0 8 16 16 16 8 0 0 0 0 8 % D
% Glu: 0 0 39 39 0 31 8 8 8 16 0 24 8 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 16 8 0 0 0 0 % F
% Gly: 39 8 8 8 31 24 47 0 24 8 0 0 16 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 62 0 % H
% Ile: 0 0 0 8 0 8 0 0 0 0 24 0 16 8 0 % I
% Lys: 0 24 8 0 8 0 8 8 8 0 0 31 0 16 16 % K
% Leu: 8 8 0 24 16 0 0 0 0 0 47 0 0 0 8 % L
% Met: 0 0 0 0 31 0 0 0 8 0 8 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 16 % N
% Pro: 0 8 0 0 0 0 0 0 16 31 0 0 0 8 54 % P
% Gln: 8 0 8 0 0 0 0 0 8 0 0 8 0 0 0 % Q
% Arg: 8 0 24 8 8 0 0 0 0 8 0 16 0 0 0 % R
% Ser: 0 0 8 0 0 0 0 8 8 8 0 0 0 0 0 % S
% Thr: 24 8 0 8 0 0 16 0 0 0 8 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 47 8 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _