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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDPK2
All Species:
12.42
Human Site:
Y346
Identified Species:
22.78
UniProt:
Q6A1A2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6A1A2
XP_002343452
396
44765
Y346
S
E
D
D
E
D
C
Y
G
N
V
S
W
P
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537000
560
63701
Y377
S
E
D
D
E
D
C
Y
G
N
Y
D
N
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2A0
559
63740
Y376
S
E
D
D
E
D
C
Y
G
N
Y
D
N
L
L
Rat
Rattus norvegicus
O55173
559
63591
Y376
S
E
D
D
E
D
C
Y
G
N
Y
D
N
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518589
320
36424
D274
L
P
A
M
S
E
D
D
E
D
C
Y
G
N
I
Chicken
Gallus gallus
Q6U1I9
432
48872
R384
V
S
G
P
S
D
L
R
H
F
D
P
E
F
T
Frog
Xenopus laevis
Q6GPN6
434
49096
H387
S
G
P
S
D
L
Q
H
F
D
P
E
F
T
E
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
H386
T
G
P
N
D
L
R
H
F
D
P
E
F
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
D554
D
T
D
T
R
Y
F
D
K
E
F
T
G
E
S
Honey Bee
Apis mellifera
XP_394208
537
61368
S369
S
E
N
E
E
L
R
S
Q
Y
R
V
P
D
H
Nematode Worm
Caenorhab. elegans
Q9Y1J3
636
71898
S395
F
G
E
P
E
Y
Y
S
N
I
G
P
V
E
P
Sea Urchin
Strong. purpuratus
XP_786576
539
61612
Y378
G
E
E
I
H
S
E
Y
Y
V
D
D
F
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12236
1081
121642
K831
D
K
S
E
S
N
N
K
G
S
S
V
F
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
62.8
N.A.
62.9
63.1
N.A.
69.4
31
31.1
31.1
N.A.
23.2
41.5
23.7
47.5
Protein Similarity:
100
N.A.
N.A.
64.4
N.A.
64.7
64.9
N.A.
72.9
49
50.4
50.5
N.A.
37.9
53
39.7
56.5
P-Site Identity:
100
N.A.
N.A.
66.6
N.A.
66.6
66.6
N.A.
0
6.6
6.6
0
N.A.
6.6
20
6.6
13.3
P-Site Similarity:
100
N.A.
N.A.
66.6
N.A.
66.6
66.6
N.A.
13.3
6.6
33.3
40
N.A.
13.3
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
31
0
0
0
8
0
0
0
0
% C
% Asp:
16
0
39
31
16
39
8
16
0
24
16
31
0
16
8
% D
% Glu:
0
47
16
16
47
8
8
0
8
8
0
16
8
16
8
% E
% Phe:
8
0
0
0
0
0
8
0
16
8
8
0
31
8
0
% F
% Gly:
8
24
8
0
0
0
0
0
39
0
8
0
16
0
16
% G
% His:
0
0
0
0
8
0
0
16
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
24
8
0
0
0
0
0
0
24
31
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
8
0
8
31
0
0
24
8
0
% N
% Pro:
0
8
16
16
0
0
0
0
0
0
16
16
8
8
8
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
16
8
0
0
8
0
0
0
0
% R
% Ser:
47
8
8
8
24
8
0
16
0
8
8
8
0
8
8
% S
% Thr:
8
8
0
8
0
0
0
0
0
0
0
8
0
16
8
% T
% Val:
8
0
0
0
0
0
0
0
0
8
8
16
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
16
8
39
8
8
24
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _