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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEATR6 All Species: 12.42
Human Site: S1141 Identified Species: 24.85
UniProt: Q6AI08 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6AI08 NP_071353.4 1181 128781 S1141 M A L K H M G S I Q A P T G D
Chimpanzee Pan troglodytes XP_001140673 1181 128587 S1141 M A L K H V G S I Q A P T G D
Rhesus Macaque Macaca mulatta XP_001115127 952 103235 A917 M G S I Q A P A G D T A R R T
Dog Lupus familis XP_537718 1182 128995 S1141 T A L E H I S S I Q A L A G N
Cat Felis silvestris
Mouse Mus musculus Q6P1G0 1184 128904 R1144 V A L K H I H R V Q T L A G D
Rat Rattus norvegicus A1EC95 1252 136487 S1212 V A L R H I H S V Q A L A G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509279 1130 123255 G1095 R A L E H I R G I Q E Q V A S
Chicken Gallus gallus XP_415906 1161 126733 L1126 L K G A I E H L H G V E K H P
Frog Xenopus laevis Q7ZY56 1174 130030 E1139 K M L Q R A I E H I R G F E E
Zebra Danio Brachydanio rerio A9JRI0 1201 130485 R1153 L L T D T L T R L K G L L G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569860 940 104465 P905 I V P E Q S D P L F T C S P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_195525 1165 129381 S1125 G S S G T S T S G G K Q K K E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 77.9 88.6 N.A. 83.6 78.7 N.A. 70.2 67.5 64 54.4 N.A. 25.7 N.A. N.A. N.A.
Protein Similarity: 100 99.3 79.2 93 N.A. 90.1 85.8 N.A. 79.7 78.4 76.5 71.9 N.A. 42 N.A. N.A. N.A.
P-Site Identity: 100 93.3 6.6 53.3 N.A. 46.6 53.3 N.A. 33.3 0 6.6 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 73.3 N.A. 66.6 80 N.A. 46.6 6.6 20 40 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 0 9 0 17 0 9 0 0 34 9 25 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 9 0 0 9 0 0 9 0 0 0 0 34 % D
% Glu: 0 0 0 25 0 9 0 9 0 0 9 9 0 9 25 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % F
% Gly: 9 9 9 9 0 0 17 9 17 17 9 9 0 50 0 % G
% His: 0 0 0 0 50 0 25 0 17 0 0 0 0 9 0 % H
% Ile: 9 0 0 9 9 34 9 0 34 9 0 0 0 0 0 % I
% Lys: 9 9 0 25 0 0 0 0 0 9 9 0 17 9 0 % K
% Leu: 17 9 59 0 0 9 0 9 17 0 0 34 9 0 9 % L
% Met: 25 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 9 0 0 0 9 9 0 0 0 17 0 9 9 % P
% Gln: 0 0 0 9 17 0 0 0 0 50 0 17 0 0 0 % Q
% Arg: 9 0 0 9 9 0 9 17 0 0 9 0 9 9 0 % R
% Ser: 0 9 17 0 0 17 9 42 0 0 0 0 9 0 9 % S
% Thr: 9 0 9 0 17 0 17 0 0 0 25 0 17 0 9 % T
% Val: 17 9 0 0 0 9 0 0 17 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _