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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR6
All Species:
10.61
Human Site:
S337
Identified Species:
21.21
UniProt:
Q6AI08
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AI08
NP_071353.4
1181
128781
S337
E
E
E
E
K
E
S
S
G
E
I
E
A
A
P
Chimpanzee
Pan troglodytes
XP_001140673
1181
128587
S337
E
E
E
E
K
E
S
S
G
E
I
E
A
A
P
Rhesus Macaque
Macaca mulatta
XP_001115127
952
103235
S131
L
H
E
G
N
T
W
S
P
S
S
L
G
V
Q
Dog
Lupus familis
XP_537718
1182
128995
S337
G
E
E
E
E
E
E
S
S
G
E
R
E
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1G0
1184
128904
C340
E
E
E
E
E
E
P
C
G
E
V
E
A
A
P
Rat
Rattus norvegicus
A1EC95
1252
136487
Y409
K
A
E
E
E
E
P
Y
G
E
V
D
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509279
1130
123255
E298
S
G
E
E
A
K
E
E
P
D
D
D
V
G
A
Chicken
Gallus gallus
XP_415906
1161
126733
G324
K
G
E
F
A
E
E
G
K
E
D
L
C
D
T
Frog
Xenopus laevis
Q7ZY56
1174
130030
L345
G
E
E
S
K
E
E
L
K
N
E
I
G
A
E
Zebra Danio
Brachydanio rerio
A9JRI0
1201
130485
K345
A
S
Q
Q
K
K
R
K
S
R
G
K
G
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569860
940
104465
G119
V
Q
C
Y
L
Q
Y
G
A
E
G
E
T
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195525
1165
129381
D308
V
S
D
V
V
H
N
D
K
H
L
N
V
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
77.9
88.6
N.A.
83.6
78.7
N.A.
70.2
67.5
64
54.4
N.A.
25.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
79.2
93
N.A.
90.1
85.8
N.A.
79.7
78.4
76.5
71.9
N.A.
42
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
33.3
N.A.
73.3
53.3
N.A.
13.3
20
33.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
40
N.A.
86.6
80
N.A.
33.3
26.6
33.3
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
17
0
0
0
9
0
0
0
34
42
17
% A
% Cys:
0
0
9
0
0
0
0
9
0
0
0
0
9
0
0
% C
% Asp:
0
0
9
0
0
0
0
9
0
9
17
17
0
9
0
% D
% Glu:
25
42
75
50
25
59
34
9
0
50
17
34
9
0
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
17
0
9
0
0
0
17
34
9
17
0
25
9
0
% G
% His:
0
9
0
0
0
9
0
0
0
9
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
0
% I
% Lys:
17
0
0
0
34
17
0
9
25
0
0
9
0
17
9
% K
% Leu:
9
0
0
0
9
0
0
9
0
0
9
17
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
9
0
0
9
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
17
0
17
0
0
0
0
0
34
% P
% Gln:
0
9
9
9
0
9
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
9
0
0
9
0
9
0
0
0
% R
% Ser:
9
17
0
9
0
0
17
34
17
9
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% T
% Val:
17
0
0
9
9
0
0
0
0
0
17
0
17
17
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _