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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEATR6 All Species: 3.94
Human Site: S385 Identified Species: 7.88
UniProt: Q6AI08 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6AI08 NP_071353.4 1181 128781 S385 E K D G V S S S F S S S S W K
Chimpanzee Pan troglodytes XP_001140673 1181 128587 P385 E K D G V S S P F T S S S W K
Rhesus Macaque Macaca mulatta XP_001115127 952 103235 M179 Y S D A E G G M Q S K M R S Y
Dog Lupus familis XP_537718 1182 128995 P385 G K D R V S P P F R S A S W K
Cat Felis silvestris
Mouse Mus musculus Q6P1G0 1184 128904 P388 G R E Q A S L P F A S S S W K
Rat Rattus norvegicus A1EC95 1252 136487 P457 G R E Q V S S P F T I S S W K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509279 1130 123255 S346 P A G K N R G S S C F S N W K
Chicken Gallus gallus XP_415906 1161 126733 P372 P A G K D P L P S H G T S W K
Frog Xenopus laevis Q7ZY56 1174 130030 S393 Q V G K D H F S P Q V Q R Y K
Zebra Danio Brachydanio rerio A9JRI0 1201 130485 T393 L T S P S V A T P Q L Y P S W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569860 940 104465 M167 R K N K V R K M R S L A K Q R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_195525 1165 129381 S356 S S S W R R L S A H D S G S S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 77.9 88.6 N.A. 83.6 78.7 N.A. 70.2 67.5 64 54.4 N.A. 25.7 N.A. N.A. N.A.
Protein Similarity: 100 99.3 79.2 93 N.A. 90.1 85.8 N.A. 79.7 78.4 76.5 71.9 N.A. 42 N.A. N.A. N.A.
P-Site Identity: 100 86.6 13.3 60 N.A. 46.6 53.3 N.A. 26.6 20 13.3 0 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 13.3 66.6 N.A. 66.6 73.3 N.A. 33.3 26.6 26.6 13.3 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 9 9 0 9 0 9 9 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 34 0 17 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 17 0 17 0 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 42 0 9 0 0 0 0 % F
% Gly: 25 0 25 17 0 9 17 0 0 0 9 0 9 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 17 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 34 0 34 0 0 9 0 0 0 9 0 9 0 67 % K
% Leu: 9 0 0 0 0 0 25 0 0 0 17 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 17 0 0 0 9 0 0 0 % M
% Asn: 0 0 9 0 9 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 17 0 0 9 0 9 9 42 17 0 0 0 9 0 0 % P
% Gln: 9 0 0 17 0 0 0 0 9 17 0 9 0 9 0 % Q
% Arg: 9 17 0 9 9 25 0 0 9 9 0 0 17 0 9 % R
% Ser: 9 17 17 0 9 42 25 34 17 25 34 50 50 25 9 % S
% Thr: 0 9 0 0 0 0 0 9 0 17 0 9 0 0 0 % T
% Val: 0 9 0 0 42 9 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 59 9 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 9 0 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _