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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEATR6 All Species: 13.03
Human Site: S676 Identified Species: 26.06
UniProt: Q6AI08 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6AI08 NP_071353.4 1181 128781 S676 C S G S D A G S A A G S T Y E
Chimpanzee Pan troglodytes XP_001140673 1181 128587 S676 C S G S D A G S A A G S T Y E
Rhesus Macaque Macaca mulatta XP_001115127 952 103235 L468 E A L Q V L A L L A R G Y F S
Dog Lupus familis XP_537718 1182 128995 C676 C S G S D A G C A A G S T Y E
Cat Felis silvestris
Mouse Mus musculus Q6P1G0 1184 128904 S679 C S G S D A G S A L G S T Y E
Rat Rattus norvegicus A1EC95 1252 136487 S747 C S G S D A G S A L G S T Y E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509279 1130 123255 G636 E A S C A A G G G G L E P S P
Chicken Gallus gallus XP_415906 1161 126733 F663 C S D S D A N F P S G S V Y E
Frog Xenopus laevis Q7ZY56 1174 130030 A683 S E P S S T P A V M Y E P S P
Zebra Danio Brachydanio rerio A9JRI0 1201 130485 N684 D S D A G G S N G A P L E P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569860 940 104465 V456 Q Q P S Q N N V V N P V H T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_195525 1165 129381 L648 V S I L V Y K L L Q S A V V E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 77.9 88.6 N.A. 83.6 78.7 N.A. 70.2 67.5 64 54.4 N.A. 25.7 N.A. N.A. N.A.
Protein Similarity: 100 99.3 79.2 93 N.A. 90.1 85.8 N.A. 79.7 78.4 76.5 71.9 N.A. 42 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 93.3 N.A. 13.3 60 6.6 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 93.3 N.A. 93.3 93.3 N.A. 20 66.6 13.3 26.6 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 9 9 59 9 9 42 42 0 9 0 0 0 % A
% Cys: 50 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 0 17 0 50 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 9 0 0 0 0 0 0 0 0 0 17 9 0 59 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % F
% Gly: 0 0 42 0 9 9 50 9 17 9 50 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 9 0 9 0 17 17 17 9 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 17 9 0 9 0 0 0 0 0 % N
% Pro: 0 0 17 0 0 0 9 0 9 0 17 0 17 9 17 % P
% Gln: 9 9 0 9 9 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 9 67 9 67 9 0 9 34 0 9 9 50 0 17 17 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 0 42 9 0 % T
% Val: 9 0 0 0 17 0 0 9 17 0 0 9 17 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 9 0 9 50 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _