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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEATR6 All Species: 5.15
Human Site: T348 Identified Species: 10.3
UniProt: Q6AI08 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6AI08 NP_071353.4 1181 128781 T348 E A A P V T G T G R V N L H E
Chimpanzee Pan troglodytes XP_001140673 1181 128587 T348 E A A P V T G T G R V N L H E
Rhesus Macaque Macaca mulatta XP_001115127 952 103235 L142 L G V Q S L P L D G S G A A G
Dog Lupus familis XP_537718 1182 128995 S348 R E V A R V P S S G R E H V H
Cat Felis silvestris
Mouse Mus musculus Q6P1G0 1184 128904 M351 E A A P G L S M D Q A N V S G
Rat Rattus norvegicus A1EC95 1252 136487 M420 D A A P G L S M D Q A N T C V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509279 1130 123255 C309 D V G A E P I C G L E K L K L
Chicken Gallus gallus XP_415906 1161 126733 S335 L C D T G N E S N H G A D V L
Frog Xenopus laevis Q7ZY56 1174 130030 D356 I G A E I N K D L E K M K L C
Zebra Danio Brachydanio rerio A9JRI0 1201 130485 E356 K G K K G A G E G K Q D G E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569860 940 104465 K130 E T H L K P R K L P P A Q Q S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_195525 1165 129381 I319 N V K L S P L I S G V S K N A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 77.9 88.6 N.A. 83.6 78.7 N.A. 70.2 67.5 64 54.4 N.A. 25.7 N.A. N.A. N.A.
Protein Similarity: 100 99.3 79.2 93 N.A. 90.1 85.8 N.A. 79.7 78.4 76.5 71.9 N.A. 42 N.A. N.A. N.A.
P-Site Identity: 100 100 0 0 N.A. 33.3 26.6 N.A. 13.3 0 6.6 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 0 6.6 N.A. 46.6 40 N.A. 20 6.6 13.3 33.3 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 42 17 0 9 0 0 0 0 17 17 9 9 17 % A
% Cys: 0 9 0 0 0 0 0 9 0 0 0 0 0 9 9 % C
% Asp: 17 0 9 0 0 0 0 9 25 0 0 9 9 0 0 % D
% Glu: 34 9 0 9 9 0 9 9 0 9 9 9 0 9 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 25 9 0 34 0 25 0 34 25 9 9 9 0 17 % G
% His: 0 0 9 0 0 0 0 0 0 9 0 0 9 17 9 % H
% Ile: 9 0 0 0 9 0 9 9 0 0 0 0 0 0 0 % I
% Lys: 9 0 17 9 9 0 9 9 0 9 9 9 17 9 0 % K
% Leu: 17 0 0 17 0 25 9 9 17 9 0 0 25 9 17 % L
% Met: 0 0 0 0 0 0 0 17 0 0 0 9 0 0 0 % M
% Asn: 9 0 0 0 0 17 0 0 9 0 0 34 0 9 0 % N
% Pro: 0 0 0 34 0 25 17 0 0 9 9 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 17 9 0 9 9 0 % Q
% Arg: 9 0 0 0 9 0 9 0 0 17 9 0 0 0 0 % R
% Ser: 0 0 0 0 17 0 17 17 17 0 9 9 0 9 9 % S
% Thr: 0 9 0 9 0 17 0 17 0 0 0 0 9 0 0 % T
% Val: 0 17 17 0 17 9 0 0 0 0 25 0 9 17 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _