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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A4 All Species: 22.12
Human Site: S545 Identified Species: 40.56
UniProt: Q6AI14 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6AI14 NP_001011552.2 798 89816 S545 L P K S S I V S L Y K K L E M
Chimpanzee Pan troglodytes XP_001163482 798 89999 S545 L P K S S I V S L Y K K L E M
Rhesus Macaque Macaca mulatta XP_001108212 798 89826 S545 L P K S S I V S L Y K K L E M
Dog Lupus familis XP_531775 801 90567 S543 Q P K S S I V S L Y K K L E I
Cat Felis silvestris
Mouse Mus musculus Q8BUE1 797 90919 S545 L P K S S I V S L Y K K L E M
Rat Rattus norvegicus P26434 717 81504 L474 Q G I T I G P L V R Y L D V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514658 801 90778 S552 Q P K S S I V S L Y K K L E M
Chicken Gallus gallus Q5ZJ75 574 64115 N331 M S H Y T H H N L S P V T Q I
Frog Xenopus laevis NP_001081553 781 87800 L530 H H H W K D K L N R F N K T Y
Zebra Danio Brachydanio rerio NP_001107567 746 85353 K503 S I V S L Y K K L E L R N A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P35449 667 75263 I424 P M F I T A T I A V I Y F T V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 M292 I L F T G I V M K H Y T Y S N
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 R390 A I S I C V A R W C A V F P L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.8 59.2 N.A. 83.4 76.6 N.A. 78.1 23.8 39.4 43.6 N.A. N.A. N.A. 31.4 N.A.
Protein Similarity: 100 99.6 98.3 73.5 N.A. 89.9 81.1 N.A. 86.7 38.8 57.1 63.5 N.A. N.A. N.A. 51.7 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 0 N.A. 93.3 6.6 0 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 13.3 N.A. 93.3 40 0 26.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.4 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 8 0 8 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 0 0 47 0 % E
% Phe: 0 0 16 0 0 0 0 0 0 0 8 0 16 0 0 % F
% Gly: 0 8 0 0 8 8 0 0 0 0 0 0 0 0 0 % G
% His: 8 8 16 0 0 8 8 0 0 8 0 0 0 0 0 % H
% Ile: 8 16 8 16 8 54 0 8 0 0 8 0 0 0 16 % I
% Lys: 0 0 47 0 8 0 16 8 8 0 47 47 8 0 0 % K
% Leu: 31 8 0 0 8 0 0 16 62 0 8 8 47 0 16 % L
% Met: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 39 % M
% Asn: 0 0 0 0 0 0 0 8 8 0 0 8 8 0 8 % N
% Pro: 8 47 0 0 0 0 8 0 0 0 8 0 0 8 0 % P
% Gln: 24 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 16 0 8 0 0 8 % R
% Ser: 8 8 8 54 47 0 0 47 0 8 0 0 0 8 0 % S
% Thr: 0 0 0 16 16 0 8 0 0 0 0 8 8 16 0 % T
% Val: 0 0 8 0 0 8 54 0 8 8 0 16 0 8 8 % V
% Trp: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 8 0 0 0 47 16 8 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _