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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A4
All Species:
20.91
Human Site:
S585
Identified Species:
38.33
UniProt:
Q6AI14
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AI14
NP_001011552.2
798
89816
S585
I
Q
G
I
K
R
L
S
P
E
D
V
E
S
I
Chimpanzee
Pan troglodytes
XP_001163482
798
89999
S585
I
Q
G
I
K
R
L
S
P
E
D
V
E
S
I
Rhesus Macaque
Macaca mulatta
XP_001108212
798
89826
S585
I
Q
G
I
K
R
L
S
P
E
D
V
E
S
I
Dog
Lupus familis
XP_531775
801
90567
T583
E
E
K
I
R
K
L
T
P
G
E
M
D
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUE1
797
90919
S585
I
Q
G
I
K
R
L
S
P
E
D
V
E
S
M
Rat
Rattus norvegicus
P26434
717
81504
H514
D
V
C
G
Q
W
S
H
Y
Q
V
R
D
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514658
801
90778
S592
I
Q
G
T
K
R
L
S
P
A
D
V
E
S
M
Chicken
Gallus gallus
Q5ZJ75
574
64115
E371
F
S
F
P
H
K
F
E
M
S
F
V
I
W
C
Frog
Xenopus laevis
NP_001081553
781
87800
E570
K
Q
A
I
E
L
V
E
G
G
G
I
G
K
I
Zebra Danio
Brachydanio rerio
NP_001107567
746
85353
L543
A
S
K
H
K
K
F
L
P
S
D
V
E
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
K464
M
V
E
S
V
Y
N
K
Y
L
D
Y
M
M
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
A332
I
Y
M
G
F
D
I
A
M
E
K
H
S
W
S
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
N430
V
P
D
E
I
P
Y
N
Y
Q
M
M
T
F
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.8
59.2
N.A.
83.4
76.6
N.A.
78.1
23.8
39.4
43.6
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
100
99.6
98.3
73.5
N.A.
89.9
81.1
N.A.
86.7
38.8
57.1
63.5
N.A.
N.A.
N.A.
51.7
N.A.
P-Site Identity:
100
100
100
26.6
N.A.
93.3
0
N.A.
80
6.6
20
33.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
100
20
N.A.
86.6
13.3
40
53.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
8
0
0
8
0
0
0
0
54
0
16
0
0
% D
% Glu:
8
8
8
8
8
0
0
16
0
39
8
0
47
8
0
% E
% Phe:
8
0
8
0
8
0
16
0
0
0
8
0
0
8
8
% F
% Gly:
0
0
39
16
0
0
0
0
8
16
8
0
8
0
0
% G
% His:
0
0
0
8
8
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
47
0
0
47
8
0
8
0
0
0
0
8
8
0
39
% I
% Lys:
8
0
16
0
47
24
0
8
0
0
8
0
0
16
0
% K
% Leu:
0
0
0
0
0
8
47
8
0
8
0
0
0
0
0
% L
% Met:
8
0
8
0
0
0
0
0
16
0
8
16
8
8
24
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
8
0
8
0
0
54
0
0
0
0
0
0
% P
% Gln:
0
47
0
0
8
0
0
0
0
16
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
39
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
16
0
8
0
0
8
39
0
16
0
0
8
39
16
% S
% Thr:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% T
% Val:
8
16
0
0
8
0
8
0
0
0
8
54
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
16
8
% W
% Tyr:
0
8
0
0
0
8
8
0
24
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _