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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A4
All Species:
10.91
Human Site:
S598
Identified Species:
20
UniProt:
Q6AI14
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AI14
NP_001011552.2
798
89816
S598
S
I
R
D
I
L
T
S
N
M
Y
Q
V
R
Q
Chimpanzee
Pan troglodytes
XP_001163482
798
89999
S598
S
I
R
D
I
L
T
S
N
M
Y
Q
V
R
Q
Rhesus Macaque
Macaca mulatta
XP_001108212
798
89826
S598
S
I
R
D
I
L
T
S
N
M
Y
Q
V
R
Q
Dog
Lupus familis
XP_531775
801
90567
R596
E
I
R
E
I
L
S
R
N
L
Y
Q
I
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUE1
797
90919
R598
S
M
R
D
I
L
T
R
S
M
Y
Q
V
R
Q
Rat
Rattus norvegicus
P26434
717
81504
R527
K
F
K
K
F
D
H
R
Y
L
R
K
I
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514658
801
90778
H605
S
M
R
D
I
L
S
H
N
M
Y
Q
V
R
Q
Chicken
Gallus gallus
Q5ZJ75
574
64115
F384
W
C
I
V
L
V
L
F
G
R
A
V
N
I
F
Frog
Xenopus laevis
NP_001081553
781
87800
T583
K
I
P
S
T
V
S
T
V
S
M
Q
N
I
Q
Zebra Danio
Brachydanio rerio
NP_001107567
746
85353
K556
N
M
H
E
L
L
S
K
N
M
Y
K
I
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
A477
M
S
G
V
E
D
I
A
G
Q
K
G
H
Y
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
F345
W
S
H
L
G
F
I
F
F
S
I
L
F
I
V
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
A443
F
W
A
G
L
R
G
A
V
G
V
A
L
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.8
59.2
N.A.
83.4
76.6
N.A.
78.1
23.8
39.4
43.6
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
100
99.6
98.3
73.5
N.A.
89.9
81.1
N.A.
86.7
38.8
57.1
63.5
N.A.
N.A.
N.A.
51.7
N.A.
P-Site Identity:
100
100
100
60
N.A.
80
0
N.A.
80
0
20
40
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
26.6
N.A.
93.3
13.3
40
86.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
16
0
0
8
8
0
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
39
0
16
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
16
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
8
8
0
16
8
0
0
0
8
0
8
% F
% Gly:
0
0
8
8
8
0
8
0
16
8
0
8
0
0
0
% G
% His:
0
0
16
0
0
0
8
8
0
0
0
0
8
0
0
% H
% Ile:
0
39
8
0
47
0
16
0
0
0
8
0
24
24
8
% I
% Lys:
16
0
8
8
0
0
0
8
0
0
8
16
0
0
0
% K
% Leu:
0
0
0
8
24
54
8
0
0
16
0
8
8
8
8
% L
% Met:
8
24
0
0
0
0
0
0
0
47
8
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
47
0
0
0
16
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
54
0
0
62
% Q
% Arg:
0
0
47
0
0
8
0
24
0
8
8
0
0
54
0
% R
% Ser:
39
16
0
8
0
0
31
24
8
16
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
31
8
0
0
0
0
0
0
8
% T
% Val:
0
0
0
16
0
16
0
0
16
0
8
8
39
0
8
% V
% Trp:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
54
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _