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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A4 All Species: 21.21
Human Site: S638 Identified Species: 38.89
UniProt: Q6AI14 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6AI14 NP_001011552.2 798 89816 S638 R Q N T L R E S M R K G H S L
Chimpanzee Pan troglodytes XP_001163482 798 89999 S638 R Q N T L R E S M R K G H S L
Rhesus Macaque Macaca mulatta XP_001108212 798 89826 S638 R Q N T L R E S M R K G H S L
Dog Lupus familis XP_531775 801 90567 S636 R R H S L R E S I R K D S S L
Cat Felis silvestris
Mouse Mus musculus Q8BUE1 797 90919 S638 R Q N T L R E S M R K G Q S L
Rat Rattus norvegicus P26434 717 81504 V567 E T G L L S S V A S P T P Y Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514658 801 90778 S645 R Q H T F R E S M R K S S S L
Chicken Gallus gallus Q5ZJ75 574 64115 Y424 G L R G A I P Y A L S L H L G
Frog Xenopus laevis NP_001081553 781 87800 R623 R T N L Q K T R Q R L R S Y N
Zebra Danio Brachydanio rerio NP_001107567 746 85353 R596 T T I R S S L R S G S F H A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P35449 667 75263 R517 F D A S S I V R A Y E K I T L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 W385 M T H Q K A L W Y S G L R G A
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 L483 G G T T A G M L E V L N I K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.8 59.2 N.A. 83.4 76.6 N.A. 78.1 23.8 39.4 43.6 N.A. N.A. N.A. 31.4 N.A.
Protein Similarity: 100 99.6 98.3 73.5 N.A. 89.9 81.1 N.A. 86.7 38.8 57.1 63.5 N.A. N.A. N.A. 51.7 N.A.
P-Site Identity: 100 100 100 60 N.A. 93.3 6.6 N.A. 73.3 6.6 20 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 6.6 N.A. 80 6.6 26.6 13.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.4 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 16 8 0 0 24 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 8 0 0 0 0 0 47 0 8 0 8 0 0 0 0 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 16 8 8 8 0 8 0 0 0 8 8 31 0 8 8 % G
% His: 0 0 24 0 0 0 0 0 0 0 0 0 39 0 0 % H
% Ile: 0 0 8 0 0 16 0 0 8 0 0 0 16 0 0 % I
% Lys: 0 0 0 0 8 8 0 0 0 0 47 8 0 8 0 % K
% Leu: 0 8 0 16 47 0 16 8 0 8 16 16 0 8 54 % L
% Met: 8 0 0 0 0 0 8 0 39 0 0 0 0 0 0 % M
% Asn: 0 0 39 0 0 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 0 % P
% Gln: 0 39 0 8 8 0 0 0 8 0 0 0 8 0 8 % Q
% Arg: 54 8 8 8 0 47 0 24 0 54 0 8 8 0 0 % R
% Ser: 0 0 0 16 16 16 8 47 8 16 16 8 24 47 0 % S
% Thr: 8 31 8 47 0 0 8 0 0 0 0 8 0 8 16 % T
% Val: 0 0 0 0 0 0 8 8 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 8 8 0 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _