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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A4
All Species:
14.55
Human Site:
T731
Identified Species:
26.67
UniProt:
Q6AI14
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AI14
NP_001011552.2
798
89816
T731
S
F
G
Y
Q
R
N
T
S
Q
E
E
Y
L
G
Chimpanzee
Pan troglodytes
XP_001163482
798
89999
T731
S
F
G
Y
Q
R
N
T
S
Q
E
E
Y
L
G
Rhesus Macaque
Macaca mulatta
XP_001108212
798
89826
T731
N
S
G
Y
Q
R
N
T
S
Q
E
E
Y
L
G
Dog
Lupus familis
XP_531775
801
90567
G729
N
E
V
D
V
D
L
G
Q
G
Q
P
C
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUE1
797
90919
N731
L
S
F
S
Y
R
S
N
T
S
W
E
D
Q
A
Rat
Rattus norvegicus
P26434
717
81504
S660
T
K
N
F
R
Y
L
S
F
P
Y
S
N
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514658
801
90778
N738
L
N
L
G
I
P
R
N
P
N
Q
D
H
P
M
Chicken
Gallus gallus
Q5ZJ75
574
64115
L517
Q
Y
I
K
R
Q
D
L
K
G
F
M
W
L
D
Frog
Xenopus laevis
NP_001081553
781
87800
T716
S
V
D
T
V
N
E
T
Q
E
E
E
E
G
I
Zebra Danio
Brachydanio rerio
NP_001107567
746
85353
R689
P
N
K
M
S
H
P
R
S
K
F
R
H
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
V610
P
S
V
Q
I
T
D
V
D
G
Q
D
D
I
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
T478
P
P
G
S
G
F
R
T
K
L
R
E
F
H
K
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
S576
S
P
N
P
A
R
S
S
M
D
K
R
N
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.8
59.2
N.A.
83.4
76.6
N.A.
78.1
23.8
39.4
43.6
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
100
99.6
98.3
73.5
N.A.
89.9
81.1
N.A.
86.7
38.8
57.1
63.5
N.A.
N.A.
N.A.
51.7
N.A.
P-Site Identity:
100
100
86.6
0
N.A.
13.3
0
N.A.
0
6.6
26.6
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
26.6
26.6
N.A.
20
40
33.3
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
8
0
8
16
0
8
8
0
16
16
0
8
% D
% Glu:
0
8
0
0
0
0
8
0
0
8
31
47
8
0
0
% E
% Phe:
0
16
8
8
0
8
0
0
8
0
16
0
8
0
0
% F
% Gly:
0
0
31
8
8
0
0
8
0
24
0
0
0
8
31
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
16
8
0
% H
% Ile:
0
0
8
0
16
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
8
8
8
0
0
0
0
16
8
8
0
0
0
8
% K
% Leu:
16
0
8
0
0
0
16
8
0
8
0
0
0
39
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
8
% M
% Asn:
16
16
16
0
0
8
24
16
0
8
0
0
16
0
0
% N
% Pro:
24
16
0
8
0
8
8
0
8
8
0
8
0
16
8
% P
% Gln:
8
0
0
8
24
8
0
0
16
24
24
0
0
8
16
% Q
% Arg:
0
0
0
0
16
39
16
8
0
0
8
16
0
0
8
% R
% Ser:
31
24
0
16
8
0
16
16
31
8
0
8
0
8
0
% S
% Thr:
8
0
0
8
0
8
0
39
8
0
0
0
0
8
0
% T
% Val:
0
8
16
0
16
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% W
% Tyr:
0
8
0
24
8
8
0
0
0
0
8
0
24
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _