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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A4 All Species: 22.42
Human Site: Y528 Identified Species: 41.11
UniProt: Q6AI14 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6AI14 NP_001011552.2 798 89816 Y528 F K K F D H R Y L R K I L I R
Chimpanzee Pan troglodytes XP_001163482 798 89999 Y528 F K K F D H R Y L R K I L I R
Rhesus Macaque Macaca mulatta XP_001108212 798 89826 Y528 F K K F D H R Y L R K I L I R
Dog Lupus familis XP_531775 801 90567 Y526 F K K F D D K Y L R K L L I R
Cat Felis silvestris
Mouse Mus musculus Q8BUE1 797 90919 Y528 F K K F D H R Y L R K I L I R
Rat Rattus norvegicus P26434 717 81504 L457 K L F V T A T L V V T Y F T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514658 801 90778 Y535 F K K F D H K Y L R K V L I R
Chicken Gallus gallus Q5ZJ75 574 64115 I314 E G I S L S G I M A I L F S G
Frog Xenopus laevis NP_001081553 781 87800 G513 F L D H L L T G I E D I C G H
Zebra Danio Brachydanio rerio NP_001107567 746 85353 I486 N N R F I R K I L I R D N R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P35449 667 75263 V407 A I A Y G L V V S I P A S I T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 E275 Y F S Y M L A E G L S L S G I
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 V373 L F T E V E L V Y K P L L I I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.8 59.2 N.A. 83.4 76.6 N.A. 78.1 23.8 39.4 43.6 N.A. N.A. N.A. 31.4 N.A.
Protein Similarity: 100 99.6 98.3 73.5 N.A. 89.9 81.1 N.A. 86.7 38.8 57.1 63.5 N.A. N.A. N.A. 51.7 N.A.
P-Site Identity: 100 100 100 80 N.A. 100 0 N.A. 86.6 0 13.3 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 6.6 N.A. 100 13.3 20 33.3 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.4 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 8 8 0 0 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 8 0 47 8 0 0 0 0 8 8 0 0 0 % D
% Glu: 8 0 0 8 0 8 0 8 0 8 0 0 0 0 0 % E
% Phe: 54 16 8 54 0 0 0 0 0 0 0 0 16 0 0 % F
% Gly: 0 8 0 0 8 0 8 8 8 0 0 0 0 16 8 % G
% His: 0 0 0 8 0 39 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 8 8 0 8 0 0 16 8 16 8 39 0 62 16 % I
% Lys: 8 47 47 0 0 0 24 0 0 8 47 0 0 0 0 % K
% Leu: 8 16 0 0 16 24 8 8 54 8 0 31 54 0 0 % L
% Met: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 8 31 0 0 47 8 0 0 8 47 % R
% Ser: 0 0 8 8 0 8 0 0 8 0 8 0 16 8 0 % S
% Thr: 0 0 8 0 8 0 16 0 0 0 8 0 0 8 8 % T
% Val: 0 0 0 8 8 0 8 16 8 8 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 16 0 0 0 47 8 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _