KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WWC2
All Species:
10.91
Human Site:
S144
Identified Species:
40
UniProt:
Q6AWC2
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6AWC2
NP_079225.5
1192
133891
S144
D
A
Y
K
E
K
S
S
S
H
T
S
L
F
S
Chimpanzee
Pan troglodytes
XP_527107
1298
144791
G258
A
V
W
E
H
K
L
G
S
Q
V
S
L
V
S
Rhesus Macaque
Macaca mulatta
XP_001092580
1192
133400
S144
D
A
Y
K
E
K
S
S
S
R
T
S
L
F
S
Dog
Lupus familis
XP_540035
1095
121248
S113
K
K
M
S
G
G
Q
S
G
Y
E
L
S
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6NXJ0
1187
132601
S144
D
A
Y
K
E
K
S
S
S
H
T
S
L
F
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFG8
1288
144331
A183
Y
N
H
L
K
L
A
A
S
R
S
S
L
C
S
Honey Bee
Apis mellifera
XP_396884
1278
142650
S144
A
L
T
T
L
G
A
S
R
T
S
L
C
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
94.5
83.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
23.7
35
N.A.
N.A.
Protein Similarity:
100
60.6
96.9
85.7
N.A.
91
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
42.4
52.9
N.A.
N.A.
P-Site Identity:
100
33.3
93.3
6.6
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
13.3
N.A.
N.A.
P-Site Similarity:
100
46.6
93.3
20
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
60
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
43
0
0
0
0
29
15
0
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
15
15
0
% C
% Asp:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
15
43
0
0
0
0
0
15
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% F
% Gly:
0
0
0
0
15
29
0
15
15
0
0
0
0
0
0
% G
% His:
0
0
15
0
15
0
0
0
0
29
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
15
15
0
43
15
58
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
0
15
15
15
15
0
0
0
0
29
72
0
0
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
15
0
0
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
29
0
0
0
0
0
% R
% Ser:
0
0
0
15
0
0
43
72
72
0
29
72
15
15
86
% S
% Thr:
0
0
15
15
0
0
0
0
0
15
43
0
0
0
0
% T
% Val:
0
15
0
0
0
0
0
0
0
0
15
0
0
15
0
% V
% Trp:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
43
0
0
0
0
0
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _