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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM4D
All Species:
8.48
Human Site:
S431
Identified Species:
26.67
UniProt:
Q6B0I6
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6B0I6
NP_060509.2
523
58603
S431
H
S
S
K
K
P
S
S
T
P
S
S
T
P
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090078
523
58822
S431
H
S
S
R
K
P
S
S
T
P
S
S
T
P
G
Dog
Lupus familis
XP_542239
524
57915
P432
R
T
S
R
G
P
G
P
T
R
P
P
T
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2K5
510
57193
S417
D
D
V
Q
K
S
D
S
A
R
A
S
P
H
P
Rat
Rattus norvegicus
A1A5Q5
510
57169
L427
A
P
P
Y
P
L
G
L
S
S
P
G
H
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6L0
590
66418
D470
R
K
Q
K
R
R
Y
D
A
D
Y
D
D
D
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U297
922
105640
E697
P
S
P
R
Q
Q
S
E
T
P
R
M
P
P
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39956
796
90193
S609
H
S
Q
Q
H
S
F
S
T
P
S
T
V
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
73.4
N.A.
69.5
69.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
24.5
N.A.
Protein Similarity:
100
N.A.
98.4
81.1
N.A.
78.3
78
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
54.4
N.A.
36.3
N.A.
P-Site Identity:
100
N.A.
93.3
26.6
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
33.3
N.A.
P-Site Similarity:
100
N.A.
100
40
N.A.
33.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
0
25
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
13
0
0
0
0
13
13
0
13
0
13
13
13
0
% D
% Glu:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
0
25
0
0
0
0
13
0
0
25
% G
% His:
38
0
0
0
13
0
0
0
0
0
0
0
13
13
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
0
25
38
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
13
0
13
0
0
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% N
% Pro:
13
13
25
0
13
38
0
13
0
50
25
13
25
38
13
% P
% Gln:
0
0
25
25
13
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
25
0
0
38
13
13
0
0
0
25
13
0
0
0
13
% R
% Ser:
0
50
38
0
0
25
38
50
13
13
38
38
0
13
13
% S
% Thr:
0
13
0
0
0
0
0
0
63
0
0
13
38
0
13
% T
% Val:
0
0
13
0
0
0
0
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
13
0
0
13
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _