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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYB5R2
All Species:
14.85
Human Site:
T139
Identified Species:
27.22
UniProt:
Q6BCY4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.58
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6BCY4
NP_057313.2
276
31458
T139
L
G
I
R
P
D
Q
T
S
E
P
K
K
T
L
Chimpanzee
Pan troglodytes
XP_001166922
336
37776
T199
L
G
I
R
P
D
Q
T
S
E
P
K
K
K
L
Rhesus Macaque
Macaca mulatta
XP_001099164
468
51616
M331
L
G
I
R
P
D
H
M
S
E
P
K
K
K
L
Dog
Lupus familis
XP_542485
636
70694
T499
F
S
I
K
P
Y
K
T
S
E
P
E
K
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3KNK3
276
31342
T139
L
L
I
K
A
N
K
T
S
E
P
E
K
K
L
Rat
Rattus norvegicus
Q6AY12
276
31220
T139
L
L
I
K
T
D
K
T
S
E
P
E
K
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518224
300
33346
K163
F
D
I
H
P
N
K
K
S
P
A
E
P
R
T
Chicken
Gallus gallus
Q5ZHX7
304
33589
K167
F
M
I
K
P
D
K
K
S
E
A
Q
R
K
F
Frog
Xenopus laevis
Q5PQA4
296
32646
K159
F
A
I
R
P
D
K
K
A
E
P
K
I
K
V
Zebra Danio
Brachydanio rerio
Q0P487
309
34369
K172
F
A
I
R
P
D
K
K
S
E
A
E
V
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623086
308
34610
K171
F
S
V
K
I
L
R
K
D
P
P
T
E
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194747
350
39037
K213
F
S
I
K
A
D
K
K
S
A
P
K
K
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P17571
621
69754
R485
F
V
I
N
G
K
Q
R
H
A
S
R
L
A
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
56.6
37.5
N.A.
82.2
82.6
N.A.
55.3
62.8
60.8
56.3
N.A.
N.A.
52.2
N.A.
47.4
Protein Similarity:
100
80.6
57.4
40.8
N.A.
91.3
93.1
N.A.
71
75.6
77.6
68.9
N.A.
N.A.
70.1
N.A.
62.5
P-Site Identity:
100
93.3
80
53.3
N.A.
53.3
60
N.A.
20
33.3
46.6
40
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
100
93.3
80
73.3
N.A.
80
80
N.A.
40
60
66.6
53.3
N.A.
N.A.
33.3
N.A.
53.3
Percent
Protein Identity:
N.A.
21.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
31.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
16
0
0
0
8
16
24
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
62
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
70
0
39
8
0
0
% E
% Phe:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% F
% Gly:
0
24
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
93
0
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
47
0
8
62
47
0
0
0
39
54
62
8
% K
% Leu:
39
16
0
0
0
8
0
0
0
0
0
0
8
0
47
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
16
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
62
0
0
0
0
16
70
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
24
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
39
0
0
8
8
0
0
0
8
8
16
0
% R
% Ser:
0
24
0
0
0
0
0
0
77
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
39
0
0
0
8
0
8
8
% T
% Val:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _