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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAL All Species: 26.06
Human Site: S30 Identified Species: 38.22
UniProt: Q6DHV7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6DHV7 NP_001012987.1 355 40264 S30 L H A H L N G S I S S H T M K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106456 267 30219
Dog Lupus familis XP_544649 356 40702 S31 L H A H L N G S I S S N T M K
Cat Felis silvestris
Mouse Mus musculus Q80SY6 360 40982 S29 L H A H L N G S I S S S T M K
Rat Rattus norvegicus XP_001076480 316 35778 V19 E C F Q M F Q V I H Q L T T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509855 367 40695 S36 K R K N S A G S V I F A S A P
Chicken Gallus gallus NP_001025718 289 32321
Frog Xenopus laevis Q4V831 347 38928 S27 A H L N G S I S T A T M K K L
Zebra Danio Brachydanio rerio Q4V9P6 348 39171 S26 A H L N G S V S F E T M E K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHH7 337 37557 L29 G I K S L C D L G E R L Y G T
Honey Bee Apis mellifera XP_394309 340 38746 T27 N G S L S A D T L K E L Y K M
Nematode Worm Caenorhab. elegans Q8IG39 388 44904 S71 L H A H L S G S L S P E T I K
Sea Urchin Strong. purpuratus XP_794004 333 36770 S27 L H A H I N G S I S P S T L Q
Poplar Tree Populus trichocarpa XP_002335976 363 40858 V37 R V L G E K G V I V F S D V E
Maize Zea mays NP_001132566 383 42761 S34 L H A H L N G S V R N S T L L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_192397 355 39930 L28 R D S T L L E L A R V L G E K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 73.5 91.5 N.A. 82.5 69.3 N.A. 62.6 61.4 65 61.9 N.A. 36.9 41.1 31.9 36.6
Protein Similarity: 100 N.A. 74 96.6 N.A. 91.1 76.6 N.A. 74.6 71.5 80.8 75.4 N.A. 58.3 61.1 51 56
P-Site Identity: 100 N.A. 0 93.3 N.A. 93.3 13.3 N.A. 13.3 0 13.3 13.3 N.A. 6.6 0 66.6 66.6
P-Site Similarity: 100 N.A. 0 100 N.A. 93.3 20 N.A. 33.3 0 40 33.3 N.A. 6.6 20 86.6 86.6
Percent
Protein Identity: 35.5 32.3 N.A. 35.7 N.A. N.A.
Protein Similarity: 60 56.6 N.A. 58.3 N.A. N.A.
P-Site Identity: 13.3 60 N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 80 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 38 0 0 13 0 0 7 7 0 7 0 7 0 % A
% Cys: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 13 0 0 0 0 0 7 0 0 % D
% Glu: 7 0 0 0 7 0 7 0 0 13 7 7 7 7 7 % E
% Phe: 0 0 7 0 0 7 0 0 7 0 13 0 0 0 0 % F
% Gly: 7 7 0 7 13 0 50 0 7 0 0 0 7 7 0 % G
% His: 0 50 0 38 0 0 0 0 0 7 0 7 0 0 0 % H
% Ile: 0 7 0 0 7 0 7 0 38 7 0 0 0 7 0 % I
% Lys: 7 0 13 0 0 7 0 0 0 7 0 0 7 19 32 % K
% Leu: 38 0 19 7 44 7 0 13 13 0 0 25 0 13 19 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 13 0 19 7 % M
% Asn: 7 0 0 19 0 32 0 0 0 0 7 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 7 % P
% Gln: 0 0 0 7 0 0 7 0 0 0 7 0 0 0 7 % Q
% Arg: 13 7 0 0 0 0 0 0 0 13 7 0 0 0 0 % R
% Ser: 0 0 13 7 13 19 0 57 0 32 19 25 7 0 7 % S
% Thr: 0 0 0 7 0 0 0 7 7 0 13 0 44 7 7 % T
% Val: 0 7 0 0 0 0 7 13 13 7 7 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _