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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAL
All Species:
7.88
Human Site:
S318
Identified Species:
11.56
UniProt:
Q6DHV7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DHV7
NP_001012987.1
355
40264
S318
E
T
F
N
L
T
Q
S
Q
V
W
D
L
S
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106456
267
30219
G239
H
G
T
F
L
N
S
G
E
R
G
S
L
D
L
Dog
Lupus familis
XP_544649
356
40702
T319
E
T
F
N
L
T
Q
T
Q
V
W
D
L
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q80SY6
360
40982
F317
E
T
F
N
L
T
P
F
Q
V
W
D
L
S
Y
Rat
Rattus norvegicus
XP_001076480
316
35778
A288
E
S
I
N
Y
I
F
A
S
N
N
T
R
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509855
367
40695
A330
E
N
F
R
L
S
Q
A
Q
A
W
D
L
S
Y
Chicken
Gallus gallus
NP_001025718
289
32321
K261
L
C
M
T
S
N
I
K
T
Q
T
V
P
S
C
Frog
Xenopus laevis
Q4V831
347
38928
H308
K
T
F
N
L
T
P
H
H
V
W
D
L
S
Y
Zebra Danio
Brachydanio rerio
Q4V9P6
348
39171
E312
S
T
F
G
L
T
K
E
A
V
W
I
L
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHH7
337
37557
E301
E
T
F
G
L
T
R
E
Q
C
I
D
L
T
L
Honey Bee
Apis mellifera
XP_394309
340
38746
E306
S
T
F
N
L
S
R
E
Q
L
I
K
L
C
L
Nematode Worm
Caenorhab. elegans
Q8IG39
388
44904
T351
A
I
T
F
D
L
S
T
E
E
L
I
G
I
N
Sea Urchin
Strong. purpuratus
XP_794004
333
36770
N304
D
C
I
F
G
G
E
N
V
K
G
L
L
R
T
Poplar Tree
Populus trichocarpa
XP_002335976
363
40858
K327
T
A
F
G
L
G
K
K
E
M
F
E
L
A
R
Maize
Zea mays
NP_001132566
383
42761
F339
T
T
F
G
L
S
K
F
E
L
F
Q
L
A
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192397
355
39930
S320
R
S
L
G
L
S
K
S
E
T
F
A
L
A
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
73.5
91.5
N.A.
82.5
69.3
N.A.
62.6
61.4
65
61.9
N.A.
36.9
41.1
31.9
36.6
Protein Similarity:
100
N.A.
74
96.6
N.A.
91.1
76.6
N.A.
74.6
71.5
80.8
75.4
N.A.
58.3
61.1
51
56
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
86.6
20
N.A.
66.6
6.6
73.3
53.3
N.A.
53.3
40
0
6.6
P-Site Similarity:
100
N.A.
20
100
N.A.
86.6
33.3
N.A.
80
6.6
80
60
N.A.
66.6
60
13.3
26.6
Percent
Protein Identity:
35.5
32.3
N.A.
35.7
N.A.
N.A.
Protein Similarity:
60
56.6
N.A.
58.3
N.A.
N.A.
P-Site Identity:
20
26.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
60
66.6
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
13
7
7
0
7
0
19
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
7
0
0
0
7
7
% C
% Asp:
7
0
0
0
7
0
0
0
0
0
0
38
0
7
0
% D
% Glu:
38
0
0
0
0
0
7
19
32
7
0
7
0
0
7
% E
% Phe:
0
0
63
19
0
0
7
13
0
0
19
0
0
0
0
% F
% Gly:
0
7
0
32
7
13
0
7
0
0
13
0
7
0
0
% G
% His:
7
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
0
7
13
0
0
7
7
0
0
0
13
13
0
7
0
% I
% Lys:
7
0
0
0
0
0
25
13
0
7
0
7
0
0
0
% K
% Leu:
7
0
7
0
75
7
0
0
0
13
7
7
82
0
19
% L
% Met:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
38
0
13
0
7
0
7
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
19
0
38
7
0
7
0
0
13
% Q
% Arg:
7
0
0
7
0
0
13
0
0
7
0
0
7
7
13
% R
% Ser:
13
13
0
0
7
25
13
13
7
0
0
7
0
50
0
% S
% Thr:
13
50
13
7
0
38
0
13
7
7
7
7
0
7
7
% T
% Val:
0
0
0
0
0
0
0
0
7
32
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
38
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
32
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _