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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAL
All Species:
40
Human Site:
T269
Identified Species:
58.67
UniProt:
Q6DHV7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DHV7
NP_001012987.1
355
40264
T269
T
S
N
V
K
S
Q
T
V
P
S
Y
D
Q
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106456
267
30219
D190
P
T
V
G
Q
A
K
D
F
M
E
P
L
L
E
Dog
Lupus familis
XP_544649
356
40702
T270
T
S
N
I
K
S
Q
T
V
R
S
Y
D
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80SY6
360
40982
T268
T
S
N
I
K
S
Q
T
V
P
S
Y
D
Q
H
Rat
Rattus norvegicus
XP_001076480
316
35778
L239
M
M
T
L
W
Q
S
L
C
H
L
L
K
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509855
367
40695
T281
T
S
N
V
R
S
R
T
V
P
S
Y
D
R
H
Chicken
Gallus gallus
NP_001025718
289
32321
E212
S
E
I
P
N
Q
E
E
E
T
K
I
L
L
G
Frog
Xenopus laevis
Q4V831
347
38928
T259
T
S
N
I
K
G
Q
T
V
S
S
Y
N
E
H
Zebra Danio
Brachydanio rerio
Q4V9P6
348
39171
T263
T
S
N
V
K
G
Q
T
V
P
S
Y
D
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHH7
337
37557
T252
T
S
N
V
K
S
G
T
V
P
S
L
E
E
H
Honey Bee
Apis mellifera
XP_394309
340
38746
T257
T
S
N
V
R
C
K
T
V
P
T
Y
E
S
H
Nematode Worm
Caenorhab. elegans
Q8IG39
388
44904
T302
S
S
N
V
Y
S
K
T
T
T
N
Y
R
N
S
Sea Urchin
Strong. purpuratus
XP_794004
333
36770
T255
G
D
Q
D
L
V
D
T
V
V
R
S
N
I
P
Poplar Tree
Populus trichocarpa
XP_002335976
363
40858
S278
T
S
N
I
K
T
E
S
I
S
S
I
D
I
H
Maize
Zea mays
NP_001132566
383
42761
G290
T
S
N
V
M
T
G
G
A
P
S
L
E
L
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192397
355
39930
S271
T
S
N
I
V
T
K
S
I
S
S
I
D
I
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
73.5
91.5
N.A.
82.5
69.3
N.A.
62.6
61.4
65
61.9
N.A.
36.9
41.1
31.9
36.6
Protein Similarity:
100
N.A.
74
96.6
N.A.
91.1
76.6
N.A.
74.6
71.5
80.8
75.4
N.A.
58.3
61.1
51
56
P-Site Identity:
100
N.A.
0
86.6
N.A.
93.3
0
N.A.
80
0
66.6
86.6
N.A.
73.3
60
40
13.3
P-Site Similarity:
100
N.A.
26.6
93.3
N.A.
100
6.6
N.A.
100
13.3
86.6
93.3
N.A.
86.6
86.6
60
20
Percent
Protein Identity:
35.5
32.3
N.A.
35.7
N.A.
N.A.
Protein Similarity:
60
56.6
N.A.
58.3
N.A.
N.A.
P-Site Identity:
46.6
46.6
N.A.
40
N.A.
N.A.
P-Site Similarity:
80
60
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
0
7
7
0
0
0
0
44
0
0
% D
% Glu:
0
7
0
0
0
0
13
7
7
0
7
0
19
13
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
0
13
13
7
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
69
% H
% Ile:
0
0
7
32
0
0
0
0
13
0
0
19
0
25
0
% I
% Lys:
0
0
0
0
44
0
25
0
0
0
7
0
7
7
0
% K
% Leu:
0
0
0
7
7
0
0
7
0
0
7
19
13
19
0
% L
% Met:
7
7
0
0
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
75
0
7
0
0
0
0
0
7
0
13
7
0
% N
% Pro:
7
0
0
7
0
0
0
0
0
44
0
7
0
0
7
% P
% Gln:
0
0
7
0
7
13
32
0
0
0
0
0
0
19
0
% Q
% Arg:
0
0
0
0
13
0
7
0
0
7
7
0
7
7
7
% R
% Ser:
13
75
0
0
0
38
7
13
0
19
63
7
0
7
7
% S
% Thr:
69
7
7
0
0
19
0
63
7
13
7
0
0
0
0
% T
% Val:
0
0
7
44
7
7
0
0
57
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
50
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _