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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NXN All Species: 29.7
Human Site: S189 Identified Species: 59.39
UniProt: Q6DKJ4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6DKJ4 NP_071908.2 435 48392 S189 N G Q S L E S S S L E G S H V
Chimpanzee Pan troglodytes XP_001152479 435 48374 S189 N G Q S L E S S S L E G S H V
Rhesus Macaque Macaca mulatta XP_001085223 438 48421 S192 N G Q S L E S S S L E G S H V
Dog Lupus familis XP_853899 449 49609 S203 N G Q S L E S S S L E G S H V
Cat Felis silvestris
Mouse Mus musculus P97346 435 48326 S189 N G Q S L E S S S L E G S H V
Rat Rattus norvegicus NP_001101755 369 41034 S135 S H V G V Y F S A H W C P P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505260 199 22504
Chicken Gallus gallus
Frog Xenopus laevis Q6GM16 414 46826 S168 N S Q S Q E S S T L E G S Y V
Zebra Danio Brachydanio rerio Q503L9 418 47392 T172 N R Q T T D S T A L E G S Y V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001185464 370 41396 K142 P P C R V F T K E L K S T Y D
Poplar Tree Populus trichocarpa XP_002314537 555 63438 L184 D G K K I P V L D L E G K L V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564756 578 65151 S199 D G N K V P V S E L E G K T I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.5 95.5 N.A. 97.9 82.9 N.A. 38.1 N.A. 77.9 74.2 N.A. N.A. N.A. N.A. 32.8
Protein Similarity: 100 100 96.3 95.9 N.A. 98.8 83.9 N.A. 41.3 N.A. 86.9 87.1 N.A. N.A. N.A. N.A. 52.4
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 0 N.A. 73.3 53.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 0 N.A. 86.6 86.6 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 23.2 N.A. N.A. 25 N.A. N.A.
Protein Similarity: 38.3 N.A. N.A. 39.7 N.A. N.A.
P-Site Identity: 33.3 N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: 53.3 N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 9 % C
% Asp: 17 0 0 0 0 9 0 0 9 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 50 0 0 17 0 75 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 59 0 9 0 0 0 0 0 0 0 75 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 9 0 0 0 42 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 9 17 0 0 0 9 0 0 9 0 17 0 0 % K
% Leu: 0 0 0 0 42 0 0 9 0 84 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 59 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 9 0 0 0 17 0 0 0 0 0 0 9 9 0 % P
% Gln: 0 0 59 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 9 0 50 0 0 59 67 42 0 0 9 59 0 0 % S
% Thr: 0 0 0 9 9 0 9 9 9 0 0 0 9 9 0 % T
% Val: 0 0 9 0 25 0 17 0 0 0 0 0 0 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 25 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _