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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC19
All Species:
2.42
Human Site:
S346
Identified Species:
4.44
UniProt:
Q6DKK2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DKK2
NP_060245.2
501
55803
S346
E
L
A
E
D
I
M
S
V
E
E
K
A
N
T
Chimpanzee
Pan troglodytes
XP_511781
496
55291
E342
E
R
E
K
E
L
A
E
D
I
M
S
V
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536654
376
41759
D223
R
E
K
E
L
A
E
D
I
L
S
V
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC21
365
41216
E212
E
R
E
K
E
L
A
E
D
I
M
S
E
E
T
Rat
Rattus norvegicus
NP_001103114
352
39856
E199
E
R
E
K
E
L
A
E
D
I
M
S
E
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509278
328
37142
E175
E
R
G
R
E
L
T
E
D
D
I
P
E
E
E
Chicken
Gallus gallus
XP_415842
360
39852
D207
K
E
K
D
L
P
E
D
V
L
P
A
E
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693210
403
45086
T250
S
D
E
E
R
K
D
T
R
L
L
L
G
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609934
369
42042
K216
Q
L
A
K
L
L
E
K
M
P
D
D
K
D
I
Honey Bee
Apis mellifera
XP_001121497
275
31676
D122
D
I
Y
D
K
I
G
D
T
Q
K
A
E
N
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785756
272
30672
P119
E
K
L
L
K
D
T
P
D
D
S
T
E
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9FYT6
715
81387
S551
A
L
A
K
L
H
S
S
W
S
P
S
E
Q
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940Z1
316
35234
G163
N
L
V
R
A
Y
K
G
E
N
S
L
D
K
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
67
N.A.
62.4
60.2
N.A.
47.5
45.9
N.A.
37.3
N.A.
21.1
20.3
N.A.
21.1
Protein Similarity:
100
98.5
N.A.
71
N.A.
67.2
64.4
N.A.
57.2
58.8
N.A.
52.5
N.A.
37.5
36.3
N.A.
35.1
P-Site Identity:
100
6.6
N.A.
6.6
N.A.
13.3
6.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
26.6
N.A.
13.3
N.A.
33.3
26.6
N.A.
26.6
20
N.A.
20
N.A.
53.3
46.6
N.A.
20
Percent
Protein Identity:
N.A.
20.1
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
35.9
N.A.
34.7
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
0
8
8
24
0
0
0
0
16
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
16
8
8
8
24
39
16
8
8
8
8
0
% D
% Glu:
47
16
31
24
31
0
24
31
8
8
8
0
62
54
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
8
8
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
16
0
0
8
24
8
0
0
0
8
% I
% Lys:
8
8
16
39
16
8
8
8
0
0
8
8
8
8
16
% K
% Leu:
0
31
8
8
31
39
0
0
0
24
8
16
0
8
0
% L
% Met:
0
0
0
0
0
0
8
0
8
0
24
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
0
0
16
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
8
16
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
8
31
0
16
8
0
0
0
8
0
0
0
0
0
8
% R
% Ser:
8
0
0
0
0
0
8
16
0
8
24
31
0
0
24
% S
% Thr:
0
0
0
0
0
0
16
8
8
0
0
8
0
0
16
% T
% Val:
0
0
8
0
0
0
0
0
16
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _