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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC19 All Species: 0.91
Human Site: S375 Identified Species: 1.67
UniProt: Q6DKK2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6DKK2 NP_060245.2 501 55803 S375 L L F S K Q P S Q A Q R M Y E
Chimpanzee Pan troglodytes XP_511781 496 55291 S371 C A R Y L L F S K Q P S Q A Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536654 376 41759 K252 A R Y L L F S K Q P S Q A Q R
Cat Felis silvestris
Mouse Mus musculus Q8CC21 365 41216 K241 A R Y L L F S K Q L S Q A Q R
Rat Rattus norvegicus NP_001103114 352 39856 K228 A R Y L L F S K Q L S Q A Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509278 328 37142 R204 Y A R Y L L T R K Q L P L A Q
Chicken Gallus gallus XP_415842 360 39852 N236 A R Y L L D I N Q L S V A Q K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693210 403 45086 R279 I G A C R D Y R H A L Q I C Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609934 369 42042 L245 L M K Q G K Y L E A K N L F K
Honey Bee Apis mellifera XP_001121497 275 31676 L151 D N Q N Q D I L Q L L G L T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785756 272 30672 L148 L D A Y A R F L G A T N S L A
Poplar Tree Populus trichocarpa
Maize Zea mays Q9FYT6 715 81387 D580 R R I G R K M D G L V L L G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940Z1 316 35234 L192 G V I T Y T V L V D W M A N L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 N.A. 67 N.A. 62.4 60.2 N.A. 47.5 45.9 N.A. 37.3 N.A. 21.1 20.3 N.A. 21.1
Protein Similarity: 100 98.5 N.A. 71 N.A. 67.2 64.4 N.A. 57.2 58.8 N.A. 52.5 N.A. 37.5 36.3 N.A. 35.1
P-Site Identity: 100 6.6 N.A. 6.6 N.A. 6.6 6.6 N.A. 0 6.6 N.A. 6.6 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 20 N.A. 20 N.A. 20 20 N.A. 20 26.6 N.A. 40 N.A. 60 26.6 N.A. 20
Percent
Protein Identity: N.A. 20.1 N.A. 20.1 N.A. N.A.
Protein Similarity: N.A. 35.9 N.A. 34.7 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 16 16 0 8 0 0 0 0 31 0 0 39 16 8 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 8 0 0 0 24 0 8 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % E
% Phe: 0 0 8 0 0 24 16 0 0 0 0 0 0 8 0 % F
% Gly: 8 8 0 8 8 0 0 0 16 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 0 16 0 0 0 16 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 8 0 8 16 0 24 16 0 8 0 0 0 16 % K
% Leu: 24 8 0 31 47 16 0 31 0 39 24 8 31 8 16 % L
% Met: 0 8 0 0 0 0 8 0 0 0 0 8 8 0 0 % M
% Asn: 0 8 0 8 0 0 0 8 0 0 0 16 0 8 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 8 8 8 0 0 0 % P
% Gln: 0 0 8 8 8 8 0 0 47 16 8 31 8 31 24 % Q
% Arg: 8 39 16 0 16 8 0 16 0 0 0 8 0 0 31 % R
% Ser: 0 0 0 8 0 0 24 16 0 0 31 8 8 0 0 % S
% Thr: 0 0 0 8 0 8 8 0 0 0 8 0 0 8 0 % T
% Val: 0 8 0 0 0 0 8 0 8 0 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 8 0 31 24 8 0 16 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _