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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC19 All Species: 1.82
Human Site: S492 Identified Species: 3.33
UniProt: Q6DKK2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6DKK2 NP_060245.2 501 55803 S492 L A E L S K K S R P L T N S V
Chimpanzee Pan troglodytes XP_511781 496 55291 E487 H I R E E L A E L S K K S R P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536654 376 41759 L368 I R E E L A E L S R K S R P L
Cat Felis silvestris
Mouse Mus musculus Q8CC21 365 41216 L357 I R E E L A E L S R K S R R L
Rat Rattus norvegicus NP_001103114 352 39856 L344 I R E E L A E L S R K S R L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509278 328 37142 E320 H I K E E L A E L S R R S K G
Chicken Gallus gallus XP_415842 360 39852 L352 I Q E E L A E L A K R R K G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693210 403 45086 S395 R R N A K D N S K V E D E L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609934 369 42042 T361 Y C L N E I K T T L N G E K R
Honey Bee Apis mellifera XP_001121497 275 31676 A267 C S E G E Y L A K T R N D M I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785756 272 30672 I264 D R E A V I T I R A N L Q K V
Poplar Tree Populus trichocarpa
Maize Zea mays Q9FYT6 715 81387 L703 I L E L K R K L R Y V T R Q I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940Z1 316 35234 S308 P R A F G S G S G R V R R F N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 N.A. 67 N.A. 62.4 60.2 N.A. 47.5 45.9 N.A. 37.3 N.A. 21.1 20.3 N.A. 21.1
Protein Similarity: 100 98.5 N.A. 71 N.A. 67.2 64.4 N.A. 57.2 58.8 N.A. 52.5 N.A. 37.5 36.3 N.A. 35.1
P-Site Identity: 100 0 N.A. 6.6 N.A. 6.6 6.6 N.A. 0 6.6 N.A. 6.6 N.A. 6.6 6.6 N.A. 20
P-Site Similarity: 100 6.6 N.A. 33.3 N.A. 33.3 33.3 N.A. 13.3 20 N.A. 13.3 N.A. 13.3 40 N.A. 20
Percent
Protein Identity: N.A. 20.1 N.A. 20.1 N.A. N.A.
Protein Similarity: N.A. 35.9 N.A. 34.7 N.A. N.A.
P-Site Identity: N.A. 33.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 60 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 16 0 31 16 8 8 8 0 0 0 0 0 % A
% Cys: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 0 0 0 0 0 8 8 0 0 % D
% Glu: 0 0 62 47 31 0 31 16 0 0 8 0 16 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 8 8 0 8 0 8 0 0 8 0 8 8 % G
% His: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 39 16 0 0 0 16 0 8 0 0 0 0 0 0 16 % I
% Lys: 0 0 8 0 16 8 24 0 16 8 31 8 8 24 8 % K
% Leu: 8 8 8 16 31 16 8 39 16 8 8 8 0 16 24 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 8 8 0 0 8 0 0 0 16 8 8 0 8 % N
% Pro: 8 0 0 0 0 0 0 0 0 8 0 0 0 8 8 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 8 8 0 % Q
% Arg: 8 47 8 0 0 8 0 0 24 31 24 24 39 16 8 % R
% Ser: 0 8 0 0 8 8 0 24 24 16 0 24 16 8 8 % S
% Thr: 0 0 0 0 0 0 8 8 8 8 0 16 0 0 0 % T
% Val: 0 0 0 0 8 0 0 0 0 8 16 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _