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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC19
All Species:
10
Human Site:
T250
Identified Species:
18.33
UniProt:
Q6DKK2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DKK2
NP_060245.2
501
55803
T250
A
L
R
L
A
Y
Q
T
D
N
K
K
A
I
T
Chimpanzee
Pan troglodytes
XP_511781
496
55291
T250
A
L
R
L
A
Y
Q
T
D
N
K
K
A
I
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536654
376
41759
T139
N
R
K
A
I
T
Y
T
Y
D
L
M
A
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CC21
365
41216
Y128
D
N
R
K
A
I
T
Y
T
Y
D
L
M
A
N
Rat
Rattus norvegicus
NP_001103114
352
39856
R115
L
I
L
H
D
A
L
R
L
A
Y
E
S
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509278
328
37142
Y91
G
N
T
Q
A
I
I
Y
T
Y
D
L
M
A
N
Chicken
Gallus gallus
XP_415842
360
39852
T123
N
R
R
A
V
I
Y
T
Y
S
L
M
A
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693210
403
45086
V166
L
M
A
N
L
A
F
V
R
G
Q
L
D
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609934
369
42042
S132
R
M
A
Q
D
I
Q
S
K
D
G
I
T
Y
V
Honey Bee
Apis mellifera
XP_001121497
275
31676
Q38
S
I
L
L
I
Q
K
Q
E
F
L
K
A
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785756
272
30672
Q35
C
E
K
E
K
N
S
Q
A
L
L
Y
T
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9FYT6
715
81387
V456
V
I
Q
R
E
A
Q
V
H
D
E
Q
V
K
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940Z1
316
35234
S79
Q
A
K
E
L
K
A
S
E
E
V
Y
M
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
67
N.A.
62.4
60.2
N.A.
47.5
45.9
N.A.
37.3
N.A.
21.1
20.3
N.A.
21.1
Protein Similarity:
100
98.5
N.A.
71
N.A.
67.2
64.4
N.A.
57.2
58.8
N.A.
52.5
N.A.
37.5
36.3
N.A.
35.1
P-Site Identity:
100
100
N.A.
13.3
N.A.
13.3
0
N.A.
6.6
20
N.A.
0
N.A.
6.6
20
N.A.
0
P-Site Similarity:
100
100
N.A.
26.6
N.A.
13.3
20
N.A.
6.6
26.6
N.A.
13.3
N.A.
26.6
46.6
N.A.
6.6
Percent
Protein Identity:
N.A.
20.1
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
35.9
N.A.
34.7
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
16
16
31
24
8
0
8
8
0
0
39
24
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
16
0
0
0
16
24
16
0
8
8
8
% D
% Glu:
0
8
0
16
8
0
0
0
16
8
8
8
0
8
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
24
0
0
16
31
8
0
0
0
0
8
0
16
0
% I
% Lys:
0
0
24
8
8
8
8
0
8
0
16
24
0
8
0
% K
% Leu:
16
16
16
24
16
0
8
0
8
8
31
24
0
0
16
% L
% Met:
0
16
0
0
0
0
0
0
0
0
0
16
24
0
0
% M
% Asn:
16
16
0
8
0
8
0
0
0
16
0
0
0
24
24
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
16
0
8
31
16
0
0
8
8
0
0
8
% Q
% Arg:
8
16
31
8
0
0
0
8
8
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
16
0
8
0
0
8
0
0
% S
% Thr:
0
0
8
0
0
8
8
31
16
0
0
0
16
0
16
% T
% Val:
8
0
0
0
8
0
0
16
0
0
8
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
16
16
16
16
8
16
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _