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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC19 All Species: 6.06
Human Site: Y248 Identified Species: 11.11
UniProt: Q6DKK2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6DKK2 NP_060245.2 501 55803 Y248 H D A L R L A Y Q T D N K K A
Chimpanzee Pan troglodytes XP_511781 496 55291 Y248 H D A L R L A Y Q T D N K K A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536654 376 41759 T137 S D N R K A I T Y T Y D L M A
Cat Felis silvestris
Mouse Mus musculus Q8CC21 365 41216 I126 E S D N R K A I T Y T Y D L M
Rat Rattus norvegicus NP_001103114 352 39856 A113 A E L I L H D A L R L A Y E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509278 328 37142 I89 Q S G N T Q A I I Y T Y D L M
Chicken Gallus gallus XP_415842 360 39852 I121 A D N R R A V I Y T Y S L M A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693210 403 45086 A164 Y S L M A N L A F V R G Q L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609934 369 42042 I130 A L R M A Q D I Q S K D G I T
Honey Bee Apis mellifera XP_001121497 275 31676 Q36 K R S I L L I Q K Q E F L K A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785756 272 30672 N33 V M C E K E K N S Q A L L Y T
Poplar Tree Populus trichocarpa
Maize Zea mays Q9FYT6 715 81387 A454 Q T V I Q R E A Q V H D E Q V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940Z1 316 35234 K77 E M Q A K E L K A S E E V Y M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 N.A. 67 N.A. 62.4 60.2 N.A. 47.5 45.9 N.A. 37.3 N.A. 21.1 20.3 N.A. 21.1
Protein Similarity: 100 98.5 N.A. 71 N.A. 67.2 64.4 N.A. 57.2 58.8 N.A. 52.5 N.A. 37.5 36.3 N.A. 35.1
P-Site Identity: 100 100 N.A. 20 N.A. 13.3 0 N.A. 6.6 26.6 N.A. 0 N.A. 6.6 20 N.A. 0
P-Site Similarity: 100 100 N.A. 33.3 N.A. 13.3 26.6 N.A. 6.6 33.3 N.A. 20 N.A. 26.6 46.6 N.A. 6.6
Percent
Protein Identity: N.A. 20.1 N.A. 20.1 N.A. N.A.
Protein Similarity: N.A. 35.9 N.A. 34.7 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 40 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 16 8 16 16 31 24 8 0 8 8 0 0 39 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 31 8 0 0 0 16 0 0 0 16 24 16 0 8 % D
% Glu: 16 8 0 8 0 16 8 0 0 0 16 8 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 8 8 0 0 % G
% His: 16 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 24 0 0 16 31 8 0 0 0 0 8 0 % I
% Lys: 8 0 0 0 24 8 8 8 8 0 8 0 16 24 0 % K
% Leu: 0 8 16 16 16 24 16 0 8 0 8 8 31 24 0 % L
% Met: 0 16 0 16 0 0 0 0 0 0 0 0 0 16 24 % M
% Asn: 0 0 16 16 0 8 0 8 0 0 0 16 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 16 0 8 0 8 16 0 8 31 16 0 0 8 8 0 % Q
% Arg: 0 8 8 16 31 8 0 0 0 8 8 0 0 0 0 % R
% Ser: 8 24 8 0 0 0 0 0 8 16 0 8 0 0 8 % S
% Thr: 0 8 0 0 8 0 0 8 8 31 16 0 0 0 16 % T
% Val: 8 0 8 0 0 0 8 0 0 16 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 16 16 16 16 16 8 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _