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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC19 All Species: 0.91
Human Site: Y381 Identified Species: 1.67
UniProt: Q6DKK2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6DKK2 NP_060245.2 501 55803 Y381 P S Q A Q R M Y E K A L Q I S
Chimpanzee Pan troglodytes XP_511781 496 55291 A377 F S K Q P S Q A Q R M Y E K A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536654 376 41759 Q258 S K Q P S Q A Q R M Y E K A L
Cat Felis silvestris
Mouse Mus musculus Q8CC21 365 41216 Q247 S K Q L S Q A Q R M Y E K A L
Rat Rattus norvegicus NP_001103114 352 39856 Q234 S K Q L S Q A Q R M Y E K A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509278 328 37142 A210 T R K Q L P L A Q K M Y E K A
Chicken Gallus gallus XP_415842 360 39852 Q242 I N Q L S V A Q K M Y E K A L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693210 403 45086 C285 Y R H A L Q I C Q E E Q G E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609934 369 42042 F251 Y L E A K N L F K E A F D T L
Honey Bee Apis mellifera XP_001121497 275 31676 T157 I L Q L L G L T L E K Y A S M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785756 272 30672 L154 F L G A T N S L A E A E R M Y
Poplar Tree Populus trichocarpa
Maize Zea mays Q9FYT6 715 81387 G586 M D G L V L L G R R G I F D G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940Z1 316 35234 N198 V L V D W M A N L G L I E E A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 N.A. 67 N.A. 62.4 60.2 N.A. 47.5 45.9 N.A. 37.3 N.A. 21.1 20.3 N.A. 21.1
Protein Similarity: 100 98.5 N.A. 71 N.A. 67.2 64.4 N.A. 57.2 58.8 N.A. 52.5 N.A. 37.5 36.3 N.A. 35.1
P-Site Identity: 100 6.6 N.A. 6.6 N.A. 6.6 6.6 N.A. 6.6 6.6 N.A. 13.3 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 40 N.A. 20 N.A. 20 20 N.A. 40 26.6 N.A. 40 N.A. 53.3 20 N.A. 33.3
Percent
Protein Identity: N.A. 20.1 N.A. 20.1 N.A. N.A.
Protein Similarity: N.A. 35.9 N.A. 34.7 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 31 0 0 39 16 8 0 24 0 8 31 24 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 0 0 0 0 0 8 8 0 % D
% Glu: 0 0 8 0 0 0 0 0 8 31 8 39 24 16 0 % E
% Phe: 16 0 0 0 0 0 0 8 0 0 0 8 8 0 0 % F
% Gly: 0 0 16 0 0 8 0 8 0 8 8 0 8 0 8 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 0 0 0 0 8 0 0 0 0 16 0 8 0 % I
% Lys: 0 24 16 0 8 0 0 0 16 16 8 0 31 16 0 % K
% Leu: 0 31 0 39 24 8 31 8 16 0 8 8 0 0 39 % L
% Met: 8 0 0 0 0 8 8 0 0 31 16 0 0 8 8 % M
% Asn: 0 8 0 0 0 16 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 8 8 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 47 16 8 31 8 31 24 0 0 8 8 0 0 % Q
% Arg: 0 16 0 0 0 8 0 0 31 16 0 0 8 0 0 % R
% Ser: 24 16 0 0 31 8 8 0 0 0 0 0 0 8 16 % S
% Thr: 8 0 0 0 8 0 0 8 0 0 0 0 0 8 0 % T
% Val: 8 0 8 0 8 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 0 0 0 8 0 0 31 24 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _