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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST2H2BC
All Species:
5.45
Human Site:
S119
Identified Species:
13.33
UniProt:
Q6DN03
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DN03
NP_003519
193
21472
S119
C
P
R
A
P
R
R
S
P
S
T
P
A
P
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545431
235
25453
V119
V
S
E
G
T
K
A
V
T
K
T
P
A
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P10854
126
13918
T53
L
K
Q
V
H
P
D
T
G
I
S
S
K
A
M
Rat
Rattus norvegicus
Q00715
125
13972
D52
V
L
K
Q
V
H
P
D
T
G
I
S
S
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521686
126
13962
T53
L
K
Q
V
H
P
D
T
G
I
S
S
K
A
M
Chicken
Gallus gallus
P0C1H4
126
13932
T53
L
K
Q
V
H
P
D
T
G
I
S
S
K
A
M
Frog
Xenopus laevis
P02281
126
13916
T53
L
K
Q
V
H
P
D
T
G
I
S
S
K
A
M
Zebra Danio
Brachydanio rerio
Q6PC60
126
13930
T53
L
K
Q
V
H
P
D
T
G
I
S
S
K
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27484
123
13527
D49
V
L
K
Q
V
H
P
D
T
G
V
S
S
K
A
Sea Urchin
Strong. purpuratus
P02289
124
13598
T51
L
K
Q
V
H
P
D
T
G
I
S
S
R
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
48
N.A.
51.2
49.7
N.A.
52.8
49.7
49.2
48.7
N.A.
N.A.
N.A.
39.3
39.9
Protein Similarity:
100
N.A.
N.A.
55.7
N.A.
57.5
56.4
N.A.
58.5
56.4
56.4
56.4
N.A.
N.A.
N.A.
50.2
48.7
P-Site Identity:
100
N.A.
N.A.
33.3
N.A.
0
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
N.A.
N.A.
40
N.A.
20
20
N.A.
20
20
20
20
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
0
0
0
20
60
20
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
60
20
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
60
20
0
0
0
0
0
% G
% His:
0
0
0
0
60
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
60
10
0
0
0
0
% I
% Lys:
0
60
20
0
0
10
0
0
0
10
0
0
50
20
0
% K
% Leu:
60
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
60
20
0
10
0
0
20
0
20
0
% P
% Gln:
0
0
60
20
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
10
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
0
0
0
0
0
10
0
10
60
80
20
0
20
% S
% Thr:
0
0
0
0
10
0
0
60
30
0
20
0
0
0
0
% T
% Val:
30
0
0
60
20
0
0
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _