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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST2H2BC
All Species:
6.67
Human Site:
S88
Identified Species:
16.3
UniProt:
Q6DN03
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DN03
NP_003519
193
21472
S88
L
A
H
Y
N
K
R
S
T
I
T
S
R
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545431
235
25453
S88
L
A
H
Y
N
K
R
S
T
I
T
S
R
E
I
Cat
Felis silvestris
Mouse
Mus musculus
P10854
126
13918
A22
S
K
K
A
V
T
K
A
Q
K
K
D
G
K
K
Rat
Rattus norvegicus
Q00715
125
13972
K21
G
S
K
K
A
V
T
K
A
Q
K
K
D
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521686
126
13962
A22
S
K
K
A
V
T
K
A
Q
K
K
D
G
K
K
Chicken
Gallus gallus
P0C1H4
126
13932
T22
S
K
K
A
V
T
K
T
Q
K
K
G
D
K
K
Frog
Xenopus laevis
P02281
126
13916
T22
S
K
K
A
V
T
K
T
Q
K
K
D
G
K
K
Zebra Danio
Brachydanio rerio
Q6PC60
126
13930
T22
S
K
K
A
V
T
K
T
Q
K
K
G
D
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27484
123
13527
V18
A
K
K
A
A
K
T
V
S
K
P
K
D
G
K
Sea Urchin
Strong. purpuratus
P02289
124
13598
K20
K
K
A
V
K
G
T
K
T
A
X
G
G
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
48
N.A.
51.2
49.7
N.A.
52.8
49.7
49.2
48.7
N.A.
N.A.
N.A.
39.3
39.9
Protein Similarity:
100
N.A.
N.A.
55.7
N.A.
57.5
56.4
N.A.
58.5
56.4
56.4
56.4
N.A.
N.A.
N.A.
50.2
48.7
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
0
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
20
6.6
N.A.
20
20
20
20
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
10
60
20
0
0
20
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
30
40
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
0
30
40
20
0
% G
% His:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
10
% I
% Lys:
10
70
70
10
10
30
50
20
0
60
60
20
0
60
80
% K
% Leu:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
0
0
20
10
0
% R
% Ser:
50
10
0
0
0
0
0
20
10
0
0
20
0
0
10
% S
% Thr:
0
0
0
0
0
50
30
30
30
0
20
0
0
0
0
% T
% Val:
0
0
0
10
50
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _