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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQSEC1
All Species:
10.91
Human Site:
S21
Identified Species:
30
UniProt:
Q6DN90
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DN90
NP_001127854.1
963
108314
S21
L
L
E
L
E
L
D
S
G
V
E
G
E
A
P
Chimpanzee
Pan troglodytes
XP_516294
1034
115556
Y92
S
S
L
S
T
D
R
Y
S
V
E
G
E
A
P
Rhesus Macaque
Macaca mulatta
XP_001083503
963
108344
S21
L
L
E
L
E
L
D
S
G
V
E
G
E
A
P
Dog
Lupus familis
XP_541746
3034
332646
P2081
P
A
T
V
L
V
A
P
R
V
E
G
E
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0S2
961
107997
S21
L
L
E
L
E
L
D
S
G
V
E
G
E
A
P
Rat
Rattus norvegicus
Q76M68
1194
129000
P72
P
P
G
L
V
P
P
P
S
A
P
L
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414318
1243
140561
V109
D
P
T
P
T
A
S
V
F
T
E
V
S
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922323
1378
154711
E262
G
L
L
V
L
G
N
E
K
L
V
V
L
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396854
1053
118476
V40
S
S
K
S
S
R
I
V
T
V
Q
E
K
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.8
99.5
29.6
N.A.
95.6
33.6
N.A.
N.A.
67.9
N.A.
59.7
N.A.
N.A.
31.5
N.A.
N.A.
Protein Similarity:
100
92.2
99.6
30.2
N.A.
97.4
47.7
N.A.
N.A.
72.4
N.A.
64.3
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
100
40
100
40
N.A.
100
20
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
40
100
53.3
N.A.
100
20
N.A.
N.A.
6.6
N.A.
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
12
12
0
0
12
0
0
0
67
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
12
34
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
34
0
34
0
0
12
0
0
67
12
56
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
12
0
12
0
0
12
0
0
34
0
0
56
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
12
0
0
0
0
0
12
0
0
0
12
0
0
% K
% Leu:
34
45
23
45
23
34
0
0
0
12
0
12
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% N
% Pro:
23
23
0
12
0
12
12
23
0
0
12
0
12
0
67
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
12
0
12
0
0
0
0
0
0
% R
% Ser:
23
23
0
23
12
0
12
34
23
0
0
0
12
0
0
% S
% Thr:
0
0
23
0
23
0
0
0
12
12
0
0
0
0
0
% T
% Val:
0
0
0
23
12
12
0
23
0
67
12
23
0
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _