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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST2H2BD
All Species:
6.06
Human Site:
T53
Identified Species:
12.12
UniProt:
Q6DRA6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DRA6
NP_003519
164
18018
T53
L
K
R
V
H
P
D
T
G
I
W
C
K
A
M
Chimpanzee
Pan troglodytes
XP_518287
150
16310
S39
A
P
A
P
K
K
G
S
K
K
A
V
T
K
A
Rhesus Macaque
Macaca mulatta
XP_001090500
154
17046
K44
P
A
P
K
K
G
S
K
K
A
V
T
K
A
Q
Dog
Lupus familis
XP_545431
235
25453
T53
L
K
Q
V
H
P
D
T
G
I
S
S
K
A
M
Cat
Felis silvestris
Mouse
Mus musculus
P10854
126
13918
S15
A
P
A
P
K
K
G
S
K
K
A
V
T
K
A
Rat
Rattus norvegicus
Q00715
125
13972
S15
R
P
A
P
K
K
G
S
K
K
A
V
T
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521686
126
13962
S15
A
P
A
P
K
K
G
S
K
K
A
V
T
K
A
Chicken
Gallus gallus
P0C1H4
126
13932
S15
A
P
A
P
K
K
G
S
K
K
A
V
T
K
T
Frog
Xenopus laevis
P02281
126
13916
S15
A
P
A
P
K
K
G
S
K
K
A
V
T
K
T
Zebra Danio
Brachydanio rerio
Q6PC60
126
13930
S15
A
P
A
P
K
K
G
S
K
K
A
V
T
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27484
123
13527
K12
K
P
S
A
K
G
A
K
K
A
A
K
T
V
S
Sea Urchin
Strong. purpuratus
P02289
124
13598
K13
Q
V
A
K
K
G
S
K
K
A
V
K
G
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.1
59.7
51.9
N.A.
59.1
57.3
N.A.
60.9
57.3
56.7
56
N.A.
N.A.
N.A.
45.7
46.3
Protein Similarity:
100
64
64.6
55.7
N.A.
64
62.7
N.A.
65.2
62.7
63.4
62.7
N.A.
N.A.
N.A.
54.8
53.6
P-Site Identity:
100
0
13.3
80
N.A.
0
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
6.6
13.3
86.6
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
9
67
9
0
0
9
0
0
25
67
0
0
25
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
25
59
0
17
0
0
0
9
0
0
% G
% His:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% I
% Lys:
9
17
0
17
84
59
0
25
84
59
0
17
25
59
9
% K
% Leu:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
67
9
59
0
17
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
17
59
0
0
9
9
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
0
9
67
9
25
% T
% Val:
0
9
0
17
0
0
0
0
0
0
17
59
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _