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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL5
All Species:
18.18
Human Site:
S281
Identified Species:
57.14
UniProt:
Q6EMB2
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6EMB2
NP_055887.3
1281
143577
S281
K
K
S
G
D
Y
V
S
C
D
D
P
E
V
E
Chimpanzee
Pan troglodytes
XP_001161129
1286
143919
S281
K
K
S
G
D
Y
V
S
C
D
D
P
E
V
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854090
1261
141335
S277
K
K
S
G
D
Y
V
S
C
D
D
P
E
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHB8
1328
147697
S281
K
K
S
G
D
Y
V
S
C
D
D
P
E
V
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026375
1339
149400
S283
K
K
S
G
D
Y
V
S
C
D
D
P
E
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8CVX7
778
89857
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397468
754
86065
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787270
1492
165243
K316
K
K
S
S
D
Y
V
K
C
D
D
G
D
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
N.A.
89.7
N.A.
85.6
N.A.
N.A.
N.A.
60.1
N.A.
24.7
N.A.
N.A.
27.1
N.A.
32.7
Protein Similarity:
100
97.8
N.A.
93.1
N.A.
90.8
N.A.
N.A.
N.A.
72.7
N.A.
36.3
N.A.
N.A.
39.5
N.A.
48.7
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
0
N.A.
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
0
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
75
0
0
0
0
75
75
0
13
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
63
0
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
63
0
0
0
0
0
0
0
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% I
% Lys:
75
75
0
0
0
0
0
13
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
63
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
75
13
0
0
0
63
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
75
0
0
0
0
0
0
63
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _