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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRP4
All Species:
22.73
Human Site:
S99
Identified Species:
45.45
UniProt:
Q6FHJ7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6FHJ7
NP_003005.2
346
39827
S99
D
P
I
K
P
C
K
S
V
C
Q
R
A
R
D
Chimpanzee
Pan troglodytes
XP_519048
346
39838
S99
D
P
I
K
P
C
K
S
V
C
Q
R
A
R
D
Rhesus Macaque
Macaca mulatta
Q7YRN1
346
39750
S99
D
P
I
K
P
C
K
S
V
C
Q
R
A
R
D
Dog
Lupus familis
XP_540377
347
39727
S100
D
P
I
K
P
C
K
S
V
C
Q
R
A
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1N6
351
40324
S99
D
P
I
K
P
C
K
S
V
C
Q
R
A
R
D
Rat
Rattus norvegicus
Q9JLS4
348
39744
S99
D
P
I
K
P
C
K
S
V
C
Q
R
A
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516753
194
21933
Chicken
Gallus gallus
Q9IA95
315
34985
F79
C
S
P
D
L
L
F
F
L
C
A
M
Y
A
P
Frog
Xenopus laevis
Q8AVJ9
548
61888
C111
I
P
P
C
R
S
L
C
E
R
A
R
Q
G
C
Zebra Danio
Brachydanio rerio
NP_571018
315
36013
D79
L
G
T
Q
C
S
A
D
L
L
F
F
L
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
V139
P
L
P
V
C
R
S
V
C
E
R
A
R
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786860
267
30741
L31
N
L
T
R
M
P
N
L
L
H
H
S
T
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
94.5
N.A.
91.7
91.9
N.A.
43.6
50.2
25
46.5
N.A.
20.1
N.A.
N.A.
33.2
Protein Similarity:
100
99.7
99.7
97.4
N.A.
94.5
94.5
N.A.
49.1
65.3
35.4
62.4
N.A.
31.2
N.A.
N.A.
50.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
13.3
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
13.3
13.3
N.A.
6.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
17
9
50
9
9
% A
% Cys:
9
0
0
9
17
50
0
9
9
59
0
0
0
9
9
% C
% Asp:
50
0
0
9
0
0
0
9
0
0
0
0
0
0
50
% D
% Glu:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
9
9
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% H
% Ile:
9
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
50
0
0
50
0
0
0
0
0
0
0
0
% K
% Leu:
9
17
0
0
9
9
9
9
25
9
0
0
9
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
9
59
25
0
50
9
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
50
0
9
9
0
% Q
% Arg:
0
0
0
9
9
9
0
0
0
9
9
59
9
50
0
% R
% Ser:
0
9
0
0
0
17
9
50
0
0
0
9
0
9
0
% S
% Thr:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
9
0
0
0
9
50
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _