KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRP4
All Species:
21.82
Human Site:
T297
Identified Species:
43.64
UniProt:
Q6FHJ7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6FHJ7
NP_003005.2
346
39827
T297
R
L
Q
E
Q
R
R
T
V
Q
D
K
K
K
T
Chimpanzee
Pan troglodytes
XP_519048
346
39838
T297
R
L
Q
E
Q
R
R
T
V
Q
D
K
K
K
T
Rhesus Macaque
Macaca mulatta
Q7YRN1
346
39750
T297
R
L
R
E
Q
R
R
T
I
Q
D
K
K
K
T
Dog
Lupus familis
XP_540377
347
39727
T298
R
L
R
E
Q
R
R
T
V
Q
D
K
K
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1N6
351
40324
T297
R
L
Q
E
Q
Q
R
T
I
Q
D
K
K
Q
I
Rat
Rattus norvegicus
Q9JLS4
348
39744
T297
R
L
Q
E
Q
Q
R
T
T
Q
D
K
K
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516753
194
21933
P147
Q
E
E
R
R
V
T
P
N
Q
R
I
S
G
R
Chicken
Gallus gallus
Q9IA95
315
34985
E268
L
V
E
G
S
I
A
E
K
W
K
D
R
L
G
Frog
Xenopus laevis
Q8AVJ9
548
61888
A364
L
A
A
W
A
V
P
A
V
K
T
I
T
I
L
Zebra Danio
Brachydanio rerio
NP_571018
315
36013
I268
T
A
N
D
E
Y
I
I
M
G
Y
E
N
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
L633
R
T
G
A
N
Q
A
L
I
K
Q
R
P
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786860
267
30741
D220
G
R
L
L
L
E
N
D
C
L
V
I
P
W
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
94.5
N.A.
91.7
91.9
N.A.
43.6
50.2
25
46.5
N.A.
20.1
N.A.
N.A.
33.2
Protein Similarity:
100
99.7
99.7
97.4
N.A.
94.5
94.5
N.A.
49.1
65.3
35.4
62.4
N.A.
31.2
N.A.
N.A.
50.2
P-Site Identity:
100
100
86.6
86.6
N.A.
73.3
73.3
N.A.
6.6
0
6.6
0
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
26.6
20
13.3
33.3
N.A.
33.3
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
9
9
0
17
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
9
0
0
50
9
0
0
0
% D
% Glu:
0
9
17
50
9
9
0
9
0
0
0
9
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
9
0
0
0
0
0
9
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
9
9
9
25
0
0
25
0
9
25
% I
% Lys:
0
0
0
0
0
0
0
0
9
17
9
50
50
25
0
% K
% Leu:
17
50
9
9
9
0
0
9
0
9
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
9
0
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
9
9
0
0
0
0
17
9
0
% P
% Gln:
9
0
34
0
50
25
0
0
0
59
9
0
0
17
0
% Q
% Arg:
59
9
17
9
9
34
50
0
0
0
9
9
9
9
9
% R
% Ser:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% S
% Thr:
9
9
0
0
0
0
9
50
9
0
9
0
9
0
34
% T
% Val:
0
9
0
0
0
17
0
0
34
0
9
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
9
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _