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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD5
All Species:
38.18
Human Site:
S325
Identified Species:
76.36
UniProt:
Q6GMV2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6GMV2
NP_006053.2
418
47341
S325
C
V
P
N
A
E
T
S
F
P
E
N
N
F
L
Chimpanzee
Pan troglodytes
XP_515547
415
46937
S325
C
V
P
N
A
E
T
S
F
P
E
N
N
F
L
Rhesus Macaque
Macaca mulatta
XP_001104101
418
47290
S325
C
V
P
N
A
E
T
S
F
P
E
N
N
F
L
Dog
Lupus familis
XP_533007
419
47287
T325
C
V
P
N
A
E
T
T
F
P
E
N
N
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYX3
416
47077
S324
C
V
P
N
A
E
T
S
F
P
E
N
N
F
V
Rat
Rattus norvegicus
NP_001101340
417
47050
S325
C
V
P
N
A
E
T
S
F
P
E
N
N
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIZ2
420
46949
S331
C
I
P
N
A
E
T
S
F
P
D
N
N
F
L
Frog
Xenopus laevis
Q6GPQ4
421
48201
S324
C
V
P
N
A
E
A
S
F
P
D
N
N
F
I
Zebra Danio
Brachydanio rerio
NP_001004614
300
34145
L216
S
F
P
D
N
N
F
L
L
H
L
T
A
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650955
393
45086
T307
C
V
P
N
A
C
S
T
F
P
Y
S
N
D
I
Honey Bee
Apis mellifera
XP_394075
387
44121
N304
V
N
H
S
C
V
P
N
A
I
V
E
F
P
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184412
387
44301
S300
C
V
P
N
A
E
I
S
F
L
H
N
N
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
97.1
N.A.
89.9
94.2
N.A.
N.A.
78.3
79.8
54.5
N.A.
43.7
48
N.A.
51.4
Protein Similarity:
100
99
99.2
98.8
N.A.
94.2
97.1
N.A.
N.A.
87.8
89
64.3
N.A.
61
64.3
N.A.
64.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
86.6
80
6.6
N.A.
53.3
0
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
13.3
N.A.
80
13.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
84
0
9
0
9
0
0
0
9
0
0
% A
% Cys:
84
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
17
0
0
9
0
% D
% Glu:
0
0
0
0
0
75
0
0
0
0
50
9
0
0
0
% E
% Phe:
0
9
0
0
0
0
9
0
84
0
0
0
9
67
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
9
0
0
0
0
0
0
9
9
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
0
9
0
0
0
0
17
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
9
9
9
9
0
0
9
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
84
9
9
0
9
0
0
0
75
84
0
0
% N
% Pro:
0
0
92
0
0
0
9
0
0
75
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
9
0
0
9
67
0
0
0
9
0
9
0
% S
% Thr:
0
0
0
0
0
0
59
17
0
0
0
9
0
0
9
% T
% Val:
9
75
0
0
0
9
0
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _