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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD5
All Species:
21.82
Human Site:
T225
Identified Species:
43.64
UniProt:
Q6GMV2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6GMV2
NP_006053.2
418
47341
T225
E
L
L
R
R
L
F
T
E
A
L
Y
E
E
A
Chimpanzee
Pan troglodytes
XP_515547
415
46937
T225
E
L
L
R
R
L
F
T
E
A
L
Y
E
E
A
Rhesus Macaque
Macaca mulatta
XP_001104101
418
47290
T225
E
L
L
R
R
L
F
T
E
A
L
Y
E
E
A
Dog
Lupus familis
XP_533007
419
47287
T225
E
L
L
R
R
L
F
T
E
A
L
Y
E
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYX3
416
47077
K224
E
L
L
L
G
L
F
K
E
A
L
Y
E
E
A
Rat
Rattus norvegicus
NP_001101340
417
47050
T225
E
L
L
R
R
L
F
T
E
A
L
Y
E
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIZ2
420
46949
T231
E
L
L
R
L
L
F
T
E
A
L
Y
D
E
Q
Frog
Xenopus laevis
Q6GPQ4
421
48201
V224
D
Q
L
R
R
L
F
V
D
A
L
Y
E
E
R
Zebra Danio
Brachydanio rerio
NP_001004614
300
34145
W120
Y
E
D
R
L
S
Q
W
F
T
P
E
G
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650955
393
45086
C207
E
Q
L
Y
L
A
F
C
N
A
F
T
G
E
E
Honey Bee
Apis mellifera
XP_394075
387
44121
Q208
D
V
L
R
Q
M
M
Q
K
T
I
N
I
E
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184412
387
44301
G204
Q
L
S
H
K
L
L
G
K
Q
F
E
G
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
97.1
N.A.
89.9
94.2
N.A.
N.A.
78.3
79.8
54.5
N.A.
43.7
48
N.A.
51.4
Protein Similarity:
100
99
99.2
98.8
N.A.
94.2
97.1
N.A.
N.A.
87.8
89
64.3
N.A.
61
64.3
N.A.
64.8
P-Site Identity:
100
100
100
100
N.A.
80
93.3
N.A.
N.A.
80
66.6
6.6
N.A.
33.3
20
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
80
93.3
N.A.
N.A.
86.6
80
6.6
N.A.
33.3
60
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
75
0
0
0
0
42
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% D
% Glu:
67
9
0
0
0
0
0
0
59
0
0
17
59
84
9
% E
% Phe:
0
0
0
0
0
0
75
0
9
0
17
0
0
9
9
% F
% Gly:
0
0
0
0
9
0
0
9
0
0
0
0
25
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
0
0
0
9
0
0
9
17
0
0
0
0
0
0
% K
% Leu:
0
67
84
9
25
75
9
0
0
0
67
0
0
0
0
% L
% Met:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
9
17
0
0
9
0
9
9
0
9
0
0
0
9
9
% Q
% Arg:
0
0
0
75
50
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
50
0
17
0
9
0
0
9
% T
% Val:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
0
0
0
0
67
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _