KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD5
All Species:
39.7
Human Site:
T258
Identified Species:
79.39
UniProt:
Q6GMV2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6GMV2
NP_006053.2
418
47341
T258
T
N
G
Q
G
I
G
T
S
S
L
S
Q
W
V
Chimpanzee
Pan troglodytes
XP_515547
415
46937
T258
T
N
G
Q
G
I
G
T
S
S
L
S
Q
W
V
Rhesus Macaque
Macaca mulatta
XP_001104101
418
47290
T258
T
N
G
Q
G
I
G
T
S
S
L
S
Q
W
V
Dog
Lupus familis
XP_533007
419
47287
T258
T
N
G
Q
G
I
G
T
S
S
L
S
Q
W
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYX3
416
47077
T257
T
N
G
Q
G
I
G
T
S
S
L
S
Q
W
V
Rat
Rattus norvegicus
NP_001101340
417
47050
T258
T
N
G
Q
G
I
G
T
S
S
L
S
Q
W
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIZ2
420
46949
T264
T
N
G
Q
G
I
G
T
S
S
L
S
Q
W
V
Frog
Xenopus laevis
Q6GPQ4
421
48201
T257
T
N
G
Q
G
I
G
T
S
S
L
S
Q
W
V
Zebra Danio
Brachydanio rerio
NP_001004614
300
34145
D153
S
Q
W
V
H
A
C
D
A
L
E
L
P
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650955
393
45086
T240
T
N
S
Q
G
I
A
T
S
V
L
S
Q
W
V
Honey Bee
Apis mellifera
XP_394075
387
44121
T241
T
N
G
Q
G
I
G
T
S
A
F
S
R
W
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184412
387
44301
R237
W
F
T
P
G
G
L
R
S
L
F
A
L
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
97.1
N.A.
89.9
94.2
N.A.
N.A.
78.3
79.8
54.5
N.A.
43.7
48
N.A.
51.4
Protein Similarity:
100
99
99.2
98.8
N.A.
94.2
97.1
N.A.
N.A.
87.8
89
64.3
N.A.
61
64.3
N.A.
64.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
0
N.A.
80
80
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
13.3
N.A.
80
93.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
0
9
9
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
0
75
0
92
9
75
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
84
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
17
75
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
9
0
84
0
0
0
0
0
0
0
0
75
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
9
9
0
% R
% Ser:
9
0
9
0
0
0
0
0
92
67
0
84
0
0
0
% S
% Thr:
84
0
9
0
0
0
0
84
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
84
% V
% Trp:
9
0
9
0
0
0
0
0
0
0
0
0
0
84
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _