KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD5
All Species:
4.55
Human Site:
T270
Identified Species:
9.09
UniProt:
Q6GMV2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6GMV2
NP_006053.2
418
47341
T270
Q
W
V
H
A
C
D
T
L
E
L
K
P
Q
D
Chimpanzee
Pan troglodytes
XP_515547
415
46937
T270
Q
W
V
H
A
C
D
T
L
E
L
K
P
Q
D
Rhesus Macaque
Macaca mulatta
XP_001104101
418
47290
A270
Q
W
V
H
A
C
D
A
L
E
L
K
P
Q
D
Dog
Lupus familis
XP_533007
419
47287
A270
Q
W
V
H
A
C
D
A
L
E
L
K
P
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYX3
416
47077
A269
Q
W
V
H
A
C
D
A
L
E
L
T
P
Q
D
Rat
Rattus norvegicus
NP_001101340
417
47050
A270
Q
W
V
H
A
C
D
A
L
E
L
K
P
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIZ2
420
46949
A276
Q
W
V
H
A
C
D
A
L
D
L
P
M
L
Q
Frog
Xenopus laevis
Q6GPQ4
421
48201
A269
Q
W
V
H
A
C
D
A
L
E
L
P
P
R
D
Zebra Danio
Brachydanio rerio
NP_001004614
300
34145
L165
P
R
Q
Q
R
E
Q
L
D
A
F
I
D
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650955
393
45086
D252
Q
W
V
A
K
V
S
D
L
P
L
T
D
S
E
Honey Bee
Apis mellifera
XP_394075
387
44121
A253
R
W
V
K
N
V
S
A
L
E
L
P
R
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184412
387
44301
G249
L
I
G
M
N
G
Q
G
V
G
S
S
S
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
97.1
N.A.
89.9
94.2
N.A.
N.A.
78.3
79.8
54.5
N.A.
43.7
48
N.A.
51.4
Protein Similarity:
100
99
99.2
98.8
N.A.
94.2
97.1
N.A.
N.A.
87.8
89
64.3
N.A.
61
64.3
N.A.
64.8
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
60
80
6.6
N.A.
33.3
33.3
N.A.
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
N.A.
66.6
86.6
6.6
N.A.
40
53.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
67
0
0
59
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
67
9
9
9
0
0
17
0
50
% D
% Glu:
0
0
0
0
0
9
0
0
0
67
0
0
0
9
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
0
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
9
9
0
0
0
0
0
0
42
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
9
84
0
84
0
0
17
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
9
0
25
59
0
0
% P
% Gln:
75
0
9
9
0
0
17
0
0
0
0
0
0
59
9
% Q
% Arg:
9
9
0
0
9
0
0
0
0
0
0
0
9
9
0
% R
% Ser:
0
0
0
0
0
0
17
0
0
0
9
9
9
9
9
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
0
17
0
0
0
% T
% Val:
0
0
84
0
0
17
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _