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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD5
All Species:
32.12
Human Site:
Y289
Identified Species:
64.24
UniProt:
Q6GMV2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6GMV2
NP_006053.2
418
47341
Y289
D
A
F
I
D
Q
L
Y
K
D
I
E
A
A
T
Chimpanzee
Pan troglodytes
XP_515547
415
46937
Y289
D
T
F
I
D
Q
L
Y
K
D
I
E
A
A
T
Rhesus Macaque
Macaca mulatta
XP_001104101
418
47290
Y289
D
I
F
I
D
Q
L
Y
K
D
I
E
A
A
T
Dog
Lupus familis
XP_533007
419
47287
Y289
D
A
F
I
D
Q
L
Y
K
D
I
E
A
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3TYX3
416
47077
Y288
D
T
F
I
D
Q
L
Y
K
D
I
E
A
A
T
Rat
Rattus norvegicus
NP_001101340
417
47050
Y289
D
T
F
I
D
Q
L
Y
K
D
I
E
A
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIZ2
420
46949
Y295
D
A
F
I
D
Q
L
Y
K
D
I
E
K
E
S
Frog
Xenopus laevis
Q6GPQ4
421
48201
Y288
D
A
L
I
D
Q
L
Y
K
D
I
E
K
V
T
Zebra Danio
Brachydanio rerio
NP_001004614
300
34145
T180
Y
K
D
I
D
K
E
T
G
D
F
L
N
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650955
393
45086
Y271
D
T
V
I
D
G
L
Y
A
K
V
G
E
F
A
Honey Bee
Apis mellifera
XP_394075
387
44121
I268
R
I
Q
V
D
K
L
I
D
R
I
Y
D
D
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184412
387
44301
E264
V
Y
V
H
N
C
D
E
L
D
L
E
A
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
97.1
N.A.
89.9
94.2
N.A.
N.A.
78.3
79.8
54.5
N.A.
43.7
48
N.A.
51.4
Protein Similarity:
100
99
99.2
98.8
N.A.
94.2
97.1
N.A.
N.A.
87.8
89
64.3
N.A.
61
64.3
N.A.
64.8
P-Site Identity:
100
93.3
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
80
80
20
N.A.
33.3
20
N.A.
20
P-Site Similarity:
100
93.3
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
26.6
N.A.
40
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
0
0
0
9
0
0
0
59
50
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% C
% Asp:
75
0
9
0
92
0
9
0
9
84
0
0
9
9
0
% D
% Glu:
0
0
0
0
0
0
9
9
0
0
0
75
9
17
17
% E
% Phe:
0
0
59
0
0
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
0
9
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
84
0
0
0
9
0
0
75
0
0
0
0
% I
% Lys:
0
9
0
0
0
17
0
0
67
9
0
0
17
0
0
% K
% Leu:
0
0
9
0
0
0
84
0
9
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
67
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% S
% Thr:
0
34
0
0
0
0
0
9
0
0
0
0
0
0
59
% T
% Val:
9
0
17
9
0
0
0
0
0
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
0
75
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _