KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XAF1
All Species:
4.55
Human Site:
S234
Identified Species:
11.11
UniProt:
Q6GPH4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6GPH4
NP_059993.2
301
34626
S234
S
S
K
K
A
P
R
S
K
N
K
T
L
D
P
Chimpanzee
Pan troglodytes
XP_001168151
301
34717
S234
S
S
K
K
A
P
R
S
K
N
K
T
L
D
P
Rhesus Macaque
Macaca mulatta
XP_001103678
301
34456
G234
S
S
K
K
A
P
R
G
N
N
K
T
L
D
P
Dog
Lupus familis
XP_848543
231
25683
R173
T
T
L
P
L
P
L
R
L
G
H
H
D
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5NBU8
273
31098
L215
K
Q
N
G
T
V
A
L
P
L
K
S
G
L
Q
Rat
Rattus norvegicus
Q99MM4
576
63788
A396
C
D
Q
R
P
A
T
A
N
H
R
A
M
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511695
344
39477
G222
M
A
R
K
W
Y
P
G
R
K
A
Q
G
D
L
Chicken
Gallus gallus
XP_415922
224
25748
C166
T
G
A
S
D
N
I
C
L
R
C
N
K
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301111
201
22894
V143
T
G
L
P
D
T
T
V
E
S
S
R
D
V
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_563857
192
21829
K134
E
R
Y
N
H
E
T
K
C
P
G
T
V
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
91.3
40.5
N.A.
45.8
21.7
N.A.
33.4
29.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.3
95
48.5
N.A.
61.7
32.8
N.A.
50.2
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
6.6
N.A.
6.6
0
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
20
N.A.
13.3
46.6
N.A.
33.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
25.9
N.A.
N.A.
25.5
N.A.
N.A.
Protein Similarity:
38.8
N.A.
N.A.
35.5
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
30
10
10
10
0
0
10
10
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
20
0
0
0
0
0
0
0
20
40
0
% D
% Glu:
10
0
0
0
0
10
0
0
10
0
0
0
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
20
0
10
0
0
0
20
0
10
10
0
20
0
10
% G
% His:
0
0
0
0
10
0
0
0
0
10
10
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
30
40
0
0
0
10
20
10
40
0
10
0
0
% K
% Leu:
0
0
20
0
10
0
10
10
20
10
0
0
30
10
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
10
10
0
10
0
0
20
30
0
10
0
0
0
% N
% Pro:
0
0
0
20
10
40
10
0
10
10
0
0
0
10
30
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
10
10
10
0
0
30
10
10
10
10
10
0
0
20
% R
% Ser:
30
30
0
10
0
0
0
20
0
10
10
10
0
10
10
% S
% Thr:
30
10
0
0
10
10
30
0
0
0
0
40
0
0
0
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _