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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XAF1 All Species: 10
Human Site: Y261 Identified Species: 24.44
UniProt: Q6GPH4 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6GPH4 NP_059993.2 301 34626 Y261 P R G D K A A Y D I L R R C S
Chimpanzee Pan troglodytes XP_001168151 301 34717 Y261 P R G D K A A Y D I L R R C S
Rhesus Macaque Macaca mulatta XP_001103678 301 34456 Y261 P R G D R T A Y D I L R R C S
Dog Lupus familis XP_848543 231 25683 C200 T L G G C S C C G I L L P Q P
Cat Felis silvestris
Mouse Mus musculus Q5NBU8 273 31098 C242 Y D T L Q N C C Q C R I L L P
Rat Rattus norvegicus Q99MM4 576 63788 V423 P E L S R R R V K H Q G D L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511695 344 39477 F249 A P R D E S E F D V L D S C P
Chicken Gallus gallus XP_415922 224 25748 T193 C S A T H N L T E V L A G Q S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002301111 201 22894 R170 R Q P Q D F S R K R L L F T I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_563857 192 21829 G161 N G R R R R D G N G V S N K R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 91.3 40.5 N.A. 45.8 21.7 N.A. 33.4 29.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.3 95 48.5 N.A. 61.7 32.8 N.A. 50.2 48.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 20 N.A. 0 13.3 N.A. 26.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 26.6 N.A. 6.6 20 N.A. 53.3 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 25.9 N.A. N.A. 25.5 N.A. N.A.
Protein Similarity: 38.8 N.A. N.A. 35.5 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 20 30 0 0 0 0 10 0 0 0 % A
% Cys: 10 0 0 0 10 0 20 20 0 10 0 0 0 40 0 % C
% Asp: 0 10 0 40 10 0 10 0 40 0 0 10 10 0 0 % D
% Glu: 0 10 0 0 10 0 10 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 10 0 0 % F
% Gly: 0 10 40 10 0 0 0 10 10 10 0 10 10 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 40 0 10 0 0 10 % I
% Lys: 0 0 0 0 20 0 0 0 20 0 0 0 0 10 0 % K
% Leu: 0 10 10 10 0 0 10 0 0 0 70 20 10 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 20 0 0 10 0 0 0 10 0 0 % N
% Pro: 40 10 10 0 0 0 0 0 0 0 0 0 10 0 30 % P
% Gln: 0 10 0 10 10 0 0 0 10 0 10 0 0 20 0 % Q
% Arg: 10 30 20 10 30 20 10 10 0 10 10 30 30 0 10 % R
% Ser: 0 10 0 10 0 20 10 0 0 0 0 10 10 0 50 % S
% Thr: 10 0 10 10 0 10 0 10 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 10 0 20 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 30 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _