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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPRIPL1
All Species:
5.45
Human Site:
T77
Identified Species:
12
UniProt:
Q6GPH6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6GPH6
NP_001008949.1
555
63395
T77
Q
K
A
E
N
F
W
T
G
D
T
S
S
D
Q
Chimpanzee
Pan troglodytes
XP_515630
879
97579
T401
Q
K
A
E
N
F
W
T
G
D
T
S
S
D
Q
Rhesus Macaque
Macaca mulatta
XP_001098586
555
63165
R77
Q
K
A
E
N
F
W
R
G
D
T
S
S
D
Q
Dog
Lupus familis
XP_854429
786
89240
R308
Q
K
A
E
N
F
W
R
G
D
T
S
S
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
A2ASA8
547
62198
R69
Q
K
V
E
N
F
W
R
G
D
T
S
S
D
Q
Rat
Rattus norvegicus
Q66H52
547
62530
R69
Q
K
A
E
N
F
W
R
G
D
T
S
N
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512434
561
64446
M71
A
E
K
T
A
L
E
M
A
T
E
A
G
G
R
Chicken
Gallus gallus
XP_426536
506
58131
K67
E
G
Q
E
A
A
Q
K
V
L
E
K
A
A
K
Frog
Xenopus laevis
Q6GQ81
463
51973
P57
L
I
D
R
A
T
S
P
P
S
D
K
E
A
E
Zebra Danio
Brachydanio rerio
Q567X9
539
61344
T64
Q
E
I
S
Q
N
E
T
S
V
I
G
D
Q
D
Tiger Blowfish
Takifugu rubipres
Q90XY5
534
60202
E65
E
F
S
Q
L
T
P
E
P
E
N
I
G
S
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.4
97.1
65.9
N.A.
86.4
86.8
N.A.
32
28.2
20
29.5
31.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.7
98
67.3
N.A.
91.8
91.8
N.A.
52.5
47.3
36.2
50.2
49.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
0
6.6
0
13.3
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
20
26.6
6.6
20
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
46
0
28
10
0
0
10
0
0
10
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
55
10
0
10
55
10
% D
% Glu:
19
19
0
64
0
0
19
10
0
10
19
0
10
0
19
% E
% Phe:
0
10
0
0
0
55
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
55
0
0
10
19
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
0
55
10
0
0
0
0
10
0
0
0
19
0
0
10
% K
% Leu:
10
0
0
0
10
10
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
55
10
0
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
19
0
0
0
0
0
0
% P
% Gln:
64
0
10
10
10
0
10
0
0
0
0
0
0
10
55
% Q
% Arg:
0
0
0
10
0
0
0
37
0
0
0
0
0
0
10
% R
% Ser:
0
0
10
10
0
0
10
0
10
10
0
55
46
10
0
% S
% Thr:
0
0
0
10
0
19
0
28
0
10
55
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
55
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _