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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM225
All Species:
12.73
Human Site:
T208
Identified Species:
46.67
UniProt:
Q6GV28
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6GV28
NP_001013765.1
225
25828
T208
R
S
I
V
R
A
H
T
V
N
S
L
N
K
K
Chimpanzee
Pan troglodytes
XP_001137001
225
25922
T208
R
S
I
V
R
A
H
T
V
N
S
L
N
K
K
Rhesus Macaque
Macaca mulatta
XP_001108697
229
25899
T208
R
S
I
V
R
A
H
T
V
N
S
K
E
D
I
Dog
Lupus familis
XP_852701
228
25973
V207
A
A
A
P
R
S
I
V
H
T
R
E
G
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9S2
230
26464
S208
R
S
I
V
H
V
H
S
V
T
S
K
D
G
S
Rat
Rattus norvegicus
Q6GV27
231
26579
S208
R
S
I
V
H
M
H
S
D
M
P
G
K
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520775
150
16420
A133
R
P
R
N
S
P
P
A
R
G
G
G
I
G
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
82.9
54.8
N.A.
45.2
44.1
N.A.
23.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96
88.6
71.4
N.A.
67.3
67.9
N.A.
38.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
6.6
N.A.
46.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
20
N.A.
60
46.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
15
0
0
43
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
0
0
0
15
15
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
15
15
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
15
15
29
15
29
15
% G
% His:
0
0
0
0
29
0
72
0
15
0
0
0
0
0
0
% H
% Ile:
0
0
72
0
0
0
15
0
0
0
0
0
15
0
15
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
29
15
29
29
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
29
0
0
0
% L
% Met:
0
0
0
0
0
15
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
0
0
0
43
0
0
29
0
0
% N
% Pro:
0
15
0
15
0
15
15
0
0
0
15
0
0
0
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
86
0
15
0
58
0
0
0
15
0
15
0
0
0
0
% R
% Ser:
0
72
0
0
15
15
0
29
0
0
58
0
0
15
15
% S
% Thr:
0
0
0
0
0
0
0
43
0
29
0
0
0
0
0
% T
% Val:
0
0
0
72
0
15
0
15
58
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _