KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM2
All Species:
1.21
Human Site:
S339
Identified Species:
2.96
UniProt:
Q6H9L7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6H9L7
NP_872315.2
571
63906
S339
W
S
P
W
S
P
C
S
G
N
C
S
T
G
K
Chimpanzee
Pan troglodytes
XP_525268
582
65976
T350
L
W
S
V
C
S
V
T
C
G
N
G
N
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542888
464
52096
C233
W
S
V
C
S
V
T
C
G
N
G
N
Q
K
R
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
C223
W
S
V
C
S
V
T
C
G
N
G
N
Q
K
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
T201
P
W
S
L
C
S
A
T
C
G
G
G
N
Q
K
Chicken
Gallus gallus
XP_426452
491
55855
C260
E
W
S
P
W
S
P
C
S
I
T
C
G
S
G
Frog
Xenopus laevis
Q8QFV1
449
50956
C218
W
S
V
C
S
V
T
C
G
S
G
N
Q
K
R
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
C230
W
S
P
C
S
V
S
C
G
N
G
N
Q
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
K223
R
D
R
S
K
K
D
K
F
T
E
S
T
D
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
R167
P
R
R
A
V
E
E
R
E
N
E
L
D
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.4
N.A.
39.7
N.A.
38.3
N.A.
N.A.
37.1
46.9
37.4
38.1
N.A.
N.A.
24.3
N.A.
25.3
Protein Similarity:
100
46.7
N.A.
51.8
N.A.
51.1
N.A.
N.A.
48.1
59.8
50.9
51.3
N.A.
N.A.
40.4
N.A.
41.1
P-Site Identity:
100
6.6
N.A.
33.3
N.A.
33.3
N.A.
N.A.
6.6
0
26.6
40
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
13.3
N.A.
46.6
N.A.
46.6
N.A.
N.A.
13.3
0
46.6
53.3
N.A.
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
40
20
0
10
50
20
0
10
10
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
0
0
0
10
10
0
% D
% Glu:
10
0
0
0
0
10
10
0
10
0
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
50
20
50
20
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
10
0
10
0
0
0
0
0
40
30
% K
% Leu:
10
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
50
10
40
20
0
0
% N
% Pro:
20
0
20
10
0
10
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
40
20
0
% Q
% Arg:
10
10
20
0
0
0
0
10
0
0
0
0
0
0
40
% R
% Ser:
0
50
30
10
50
30
10
10
10
10
0
20
0
10
0
% S
% Thr:
0
0
0
0
0
0
30
20
0
10
10
0
20
0
0
% T
% Val:
0
0
30
10
10
40
10
0
0
0
0
0
0
0
10
% V
% Trp:
50
30
0
10
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _