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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM2
All Species:
0
Human Site:
S443
Identified Species:
0
UniProt:
Q6H9L7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6H9L7
NP_872315.2
571
63906
S443
E
A
M
D
S
P
V
S
L
Q
D
E
H
Q
G
Chimpanzee
Pan troglodytes
XP_525268
582
65976
D454
E
V
A
Y
S
T
A
D
I
F
D
R
I
K
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542888
464
52096
I337
V
A
Y
S
T
A
D
I
F
D
R
I
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
I327
V
A
Y
S
T
A
D
I
F
D
R
I
K
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
E305
E
V
A
Y
S
S
A
E
I
Y
D
R
V
K
R
Chicken
Gallus gallus
XP_426452
491
55855
L364
A
V
Y
S
A
V
N
L
R
D
E
R
Q
G
K
Frog
Xenopus laevis
Q8QFV1
449
50956
I322
V
A
Y
S
T
A
E
I
Y
D
R
I
K
R
K
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
V334
V
A
Y
S
T
A
D
V
H
D
A
N
T
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
K327
S
N
I
F
Y
D
D
K
I
W
D
E
K
R
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
I271
Y
F
P
T
N
N
A
I
V
D
P
Q
Q
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.4
N.A.
39.7
N.A.
38.3
N.A.
N.A.
37.1
46.9
37.4
38.1
N.A.
N.A.
24.3
N.A.
25.3
Protein Similarity:
100
46.7
N.A.
51.8
N.A.
51.1
N.A.
N.A.
48.1
59.8
50.9
51.3
N.A.
N.A.
40.4
N.A.
41.1
P-Site Identity:
100
20
N.A.
6.6
N.A.
6.6
N.A.
N.A.
20
0
6.6
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
33.3
N.A.
20
N.A.
20
N.A.
N.A.
33.3
13.3
20
20
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
50
20
0
10
40
30
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
40
10
0
60
40
0
0
0
0
% D
% Glu:
30
0
0
0
0
0
10
10
0
0
10
20
0
0
0
% E
% Phe:
0
10
0
10
0
0
0
0
20
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
0
0
40
30
0
0
30
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
40
30
40
% K
% Leu:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
10
10
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
10
20
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
30
30
0
40
40
% R
% Ser:
10
0
0
50
30
10
0
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
40
10
0
0
0
0
0
0
10
0
0
% T
% Val:
40
30
0
0
0
10
10
10
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
10
0
50
20
10
0
0
0
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _