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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM2
All Species:
7.88
Human Site:
T553
Identified Species:
19.26
UniProt:
Q6H9L7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.67
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6H9L7
NP_872315.2
571
63906
T553
P
N
N
G
R
A
C
T
D
N
P
L
E
E
E
Chimpanzee
Pan troglodytes
XP_525268
582
65976
T564
P
N
N
G
Q
K
C
T
E
S
P
S
D
E
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542888
464
52096
E447
N
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
E437
N
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
T415
P
N
N
G
Q
K
C
T
E
N
P
S
D
E
D
Chicken
Gallus gallus
XP_426452
491
55855
D474
N
N
G
Q
Q
C
A
D
N
P
A
E
E
E
Y
Frog
Xenopus laevis
Q8QFV1
449
50956
E432
N
N
G
Q
K
C
T
E
N
P
S
E
D
D
Y
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
E444
N
N
G
Q
K
C
A
E
N
P
Q
D
E
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
Q437
P
N
N
E
N
A
C
Q
A
N
P
D
D
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
D381
N
N
D
R
E
C
A
D
I
P
D
L
Q
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.4
N.A.
39.7
N.A.
38.3
N.A.
N.A.
37.1
46.9
37.4
38.1
N.A.
N.A.
24.3
N.A.
25.3
Protein Similarity:
100
46.7
N.A.
51.8
N.A.
51.1
N.A.
N.A.
48.1
59.8
50.9
51.3
N.A.
N.A.
40.4
N.A.
41.1
P-Site Identity:
100
53.3
N.A.
13.3
N.A.
13.3
N.A.
N.A.
60
20
6.6
13.3
N.A.
N.A.
60
N.A.
13.3
P-Site Similarity:
100
86.6
N.A.
26.6
N.A.
26.6
N.A.
N.A.
86.6
33.3
33.3
33.3
N.A.
N.A.
66.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
30
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
60
40
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
20
10
0
10
40
40
40
20
% D
% Glu:
0
0
0
10
10
0
0
40
20
0
0
20
50
50
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
50
30
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
40
20
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
60
100
40
0
10
0
0
0
30
30
0
0
0
0
0
% N
% Pro:
40
0
0
0
0
0
0
0
0
60
40
0
0
0
0
% P
% Gln:
0
0
0
50
30
0
0
10
0
0
10
0
10
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
20
10
30
20
0
0
0
% S
% Thr:
0
0
0
0
0
0
30
30
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _