KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASTL
All Species:
12.12
Human Site:
S306
Identified Species:
38.1
UniProt:
Q6HA08
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6HA08
NP_001002036.3
431
45964
S306
G
R
S
P
A
P
A
S
L
S
L
Q
R
L
L
Chimpanzee
Pan troglodytes
XP_001144288
431
45537
S306
G
R
S
P
A
P
A
S
L
S
L
Q
R
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540167
517
55710
S296
A
R
S
P
T
P
A
S
R
P
Y
L
Q
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6HA09
435
47436
S306
G
S
S
L
T
P
A
S
I
S
R
L
Q
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P42664
514
56826
N310
N
Y
P
S
A
Y
P
N
N
A
N
C
V
W
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001072106
262
29919
K140
G
C
Y
S
S
L
G
K
E
G
Y
G
Q
V
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19269
503
56893
T362
T
T
T
T
K
K
P
T
T
T
T
T
T
T
P
Sea Urchin
Strong. purpuratus
P98069
639
71875
T457
I
T
M
P
A
N
Y
T
V
G
L
S
F
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
N.A.
58.7
N.A.
67.3
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
22.9
N.A.
N.A.
26.8
24.4
Protein Similarity:
100
96.9
N.A.
66.5
N.A.
74.9
N.A.
N.A.
N.A.
N.A.
41.4
N.A.
36.8
N.A.
N.A.
42.1
35.6
P-Site Identity:
100
100
N.A.
46.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
0
20
P-Site Similarity:
100
100
N.A.
53.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
33.3
N.A.
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
50
0
50
0
0
13
0
0
0
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
13
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
50
0
0
0
0
0
13
0
0
25
0
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
13
0
13
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
13
0
13
0
0
25
0
38
25
0
25
75
% L
% Met:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
13
0
13
13
0
13
0
0
0
0
% N
% Pro:
0
0
13
50
0
50
25
0
0
13
0
0
0
0
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
25
38
25
0
% Q
% Arg:
0
38
0
0
0
0
0
0
13
0
13
0
25
13
0
% R
% Ser:
0
13
50
25
13
0
0
50
0
38
0
13
0
0
13
% S
% Thr:
13
25
13
13
25
0
0
25
13
13
13
13
13
13
0
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
13
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% W
% Tyr:
0
13
13
0
0
13
13
0
0
0
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _